Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

Triiodothyronine (T3) and thyroxine (T4) as the main secretion products of the thyroid affect nearly every human tissue and are involved in a broad range of processes ranging from energy expenditure and lipid metabolism to glucose homeostasis. Metabolomics studies outside the focus of clinical manif...

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Bibliographic Details
Published in:	PloS one Vol. 12; no. 3; p. e0173078
Main Authors:	Friedrich, Nele, Pietzner, Maik, Cannet, Claire, Thuesen, Betina H., Hansen, Torben, Wallaschofski, Henri, Grarup, Niels, Skaaby, Tea, Budde, Kathrin, Pedersen, Oluf, Nauck, Matthias, Linneberg, Allan
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 02.03.2017 Public Library of Science (PLoS)
Subjects:	Acids Adult Alanine Arteriosclerosis Biology and Life Sciences Blood Glucose - metabolism Coffee Coffee (Beverage) Dimethylglycine Energy expenditure Energy metabolism Excretion Female Gene expression Glucose Glucose metabolism Glycine Homeostasis Hormones Humans Hyperthyroidism Hypothyroidism Iodine Laboratories Laboratory tests Lactic acid Lipid metabolism Magnetic resonance spectroscopy Male Mass spectrometry Medicine Medicine and Health Sciences Metabolism Metabolites Metabolomics Middle Aged NMR NMR spectroscopy Nuclear magnetic resonance Physical Sciences Physiology Population Population studies Prevention Proton Magnetic Resonance Spectroscopy Scientific imaging Secretion Spectroscopy Studies Thrombosis Thyroid Thyroid diseases Thyroid Function Tests Thyroid gland Thyroid hormones Thyroid-stimulating hormone Thyroxine Urinalysis Urine
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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