Synthetic viruses: a new opportunity to understand and prevent viral disease

Rapid progress in DNA synthesis and sequencing is spearheading the deliberate, large-scale genetic alteration of organisms. These new advances in DNA manipulation have been extended to the level of whole-genome synthesis, as evident from the synthesis of poliovirus, from the resurrection of the exti...

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Bibliographic Details
Published in:	Nature biotechnology Vol. 27; no. 12; pp. 1163 - 1172
Main Authors:	Wimmer, Eckard, Mueller, Steffen, Tumpey, Terrence M, Taubenberger, Jeffery K
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.12.2009 Nature Publishing Group
Subjects:	Agriculture Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Biotechnology Chemical synthesis Deoxyribonucleic acid Disease prevention DNA DNA biosynthesis DNA sequencing Endogenous retroviruses Fundamental and applied biological sciences. Psychology Gene sequencing Genetic aspects Genetic engineering Genetic Engineering - trends Genetic technics Genomes Genomics Humans Influenza Influenza virus Life Sciences Methods. Procedures. Technologies Molecular Biology - trends Mycoplasma genitalium Nucleotide sequencing Phage T7 Poliovirus Prevention Retrovirus review-article Structure-function relationships Synthesis Viral diseases Viral genetics Virus diseases Virus Diseases - prevention & control Virus Diseases - virology Virus Physiological Phenomena - genetics Viruses Viruses - chemistry United States Virus Picornaviridae Orthomyxoviridae DNA synthesis Enterovirus Reconstitution Synthetic biology Review Poliovirus Influenzavirus
ISSN:	1087-0156, 1546-1696, 1546-1696
Online Access:	Get full text
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