Sequencing Illustrates the Transcriptional Response of Legionella pneumophila during Infection and Identifies Seventy Novel Small Non-Coding RNAs

Second generation sequencing has prompted a number of groups to re-interrogate the transcriptomes of several bacterial and archaeal species. One of the central findings has been the identification of complex networks of small non-coding RNAs that play central roles in transcriptional regulation in a...

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Bibliographic Details
Published in:	PloS one Vol. 6; no. 3; p. e17570
Main Authors:	Weissenmayer, Barbara A., Prendergast, James G. D., Lohan, Amanda J., Loftus, Brendan J.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 03.03.2011 Public Library of Science (PLoS)
Subjects:	Acanthamoeba castellanii Acanthamoeba castellanii - microbiology Amoeba Analysis Antisense RNA Bacteria Base Sequence Biology Biomedical research Biosynthesis Cell survival Conserved Sequence - genetics Culture Media DNA microarrays Gene expression Gene Expression Profiling Gene Expression Regulation, Bacterial Gene regulation Genes, Bacterial - genetics Genetic aspects Genomes Genomics Growth conditions Health aspects Humans Infection Infections Intracellular Intracellular Space - microbiology Legionella Legionella pneumophila Legionella pneumophila - genetics Legionella pneumophila - growth & development Legionnaires disease Legionnaires' Disease - genetics Legionnaires' Disease - microbiology Legionnaires' disease bacterium Macrophages Medicine Metabolism Molecular Sequence Data Motility Nucleic Acid Conformation Pathogens Physiology Proteins Ribonucleic acid RNA RNA, Antisense - genetics RNA, Bacterial - genetics RNA, Small Untranslated - chemistry RNA, Small Untranslated - genetics Sequence Analysis, DNA - methods Sequences Signal transduction Species Specificity Strain Studies Time Factors Transcription Transcription (Genetics) Transcription, Genetic Up-Regulation - genetics Vibrio cholerae Vibrio harveyi Ireland
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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