Gene‐specific correlation of RNA and protein levels in human cells and tissues

An important issue for molecular biology is to establish whether transcript levels of a given gene can be used as proxies for the corresponding protein levels. Here, we have developed a targeted proteomics approach for a set of human non‐secreted proteins based on parallel reaction monitoring to mea...

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Veröffentlicht in:	Molecular systems biology Jg. 12; H. 10; S. 883 - n/a
Hauptverfasser:	Edfors, Fredrik, Danielsson, Frida, Hallström, Björn M, Käll, Lukas, Lundberg, Emma, Pontén, Fredrik, Forsström, Björn, Uhlén, Mathias
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.10.2016 EMBO Press John Wiley and Sons Inc Springer Nature
Schlagworte:	Biotechnology Bioteknologi Cell Line Cell lines Consortia Deoxyribonucleic acid DNA EMBO17 EMBO31 EMBO44 Gene Expression Gene Expression Profiling - methods Genes Genomes Genomics Human tissues Humans Laboratories Molecular biology Peptides protein quantification Proteins Proteome - genetics Proteome - metabolism Proteomics Proteomics - methods Ribonucleic acid RNA Studies targeted proteomics Transcription transcriptomics targeted proteomics transcriptomics protein quantification gene expression
ISSN:	1744-4292, 1744-4292
Online-Zugang:	Volltext
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