Detection of Alzheimer's disease signature in MR images seven years before conversion to dementia: Toward an early individual prognosis

Finding very early biomarkers of Alzheimer's Disease (AD) to aid in individual prognosis is of major interest to accelerate the development of new therapies. Among the potential biomarkers, neurodegeneration measurements from MRI are considered as good candidates but have so far not been effect...

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Veröffentlicht in:	Human Brain Mapping Jg. 36; H. 12; S. 4758 - 4770
Hauptverfasser:	Coupé, Pierrick, Fonov, Vladimir S., Bernard, Charlotte, Zandifar, Azar, Eskildsen, Simon F., Helmer, Catherine, Manjón, José V., Amieva, Hélène, Dartigues, Jean-François, Allard, Michèle, Catheline, Gwenaelle, Collins, D. Louis
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Blackwell Publishing Ltd 01.12.2015 Wiley John Wiley & Sons, Inc John Wiley and Sons Inc
Schlagworte:	[INFO.INFO-IM] Computer Science [cs]/Medical Imaging Aged Aged, 80 and over Alzheimer Alzheimer Disease Alzheimer Disease - pathology Area Under Curve Cohort Studies Computer Science Databases, Factual Databases, Factual - statistics & numerical data Dementia Dementia - pathology Disease Progression Electronic Data Processing Female Hippocampus Hippocampus - pathology Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Magnetic Resonance Imaging - methods Male Medical Imaging MRI biomarker Psychiatric Status Rating Scales Reproducibility of Results ROC Curve hippocampus MRI biomarker Alzheimer
ISSN:	1065-9471, 1097-0193, 1097-0193
Online-Zugang:	Volltext
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