Gene Therapy for Vascular Smooth Muscle Cell Proliferation After Arterial Injury

Accumulation of vascular smooth muscle cells as a consequence of arterial injury is a major feature of vascular proliferative disorders. Molecular approaches to the inhibition of smooth muscle cell proliferation in these settings could potentially limit intimal expansion. This problem was approached...

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Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) Vol. 265; no. 5173; pp. 781 - 784
Main Authors:	Ohno, Takeshi, Gordon, David, San, Hong, Pompili, Vincent J., Imperiale, Michael J., Nabel, Gary J., Nabel, Elizabeth G.
Format:	Journal Article
Language:	English
Published:	United States American Society for the Advancement of Science 05.08.1994 American Association for the Advancement of Science
Subjects:	Adenoviridae - genetics adenovirus Angioplasty, Balloon Animals Arteries Arteries - injuries Arteriosclerosis - etiology Arteriosclerosis - pathology Arteriosclerosis - therapy Balloons Catheters Cell Division Cell Survival - drug effects Cells Ganciclovir - metabolism Ganciclovir - therapeutic use Gene therapy Genetic Therapy Genetic Vectors Herpesviridae - enzymology herpesvirus Hyperplasia Infections Injuries Muscle, Smooth, Vascular - cytology Phosphatases Physical trauma Recurrence Smooth muscle myocytes Surgery Swine Thymidine Kinase - genetics Thymidine Kinase - metabolism Vascular smooth muscle
ISSN:	0036-8075, 1095-9203
Online Access:	Get full text
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