PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems

Background The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR-Cas biology, including target requirements such as the protos...

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Veröffentlicht in:	Genome Biology Jg. 22; H. 1; S. 281
Hauptverfasser:	Vink, Jochem N. A., Baijens, Jan H. L., Brouns, Stan J. J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 30.09.2021 Springer Nature B.V BMC
Schlagworte:	Adaptation Animal Genetics and Genomics Bacteria Base Sequence Bioinformatics Biomedical and Life Sciences Clustered Regularly Interspaced Short Palindromic Repeats Conserved Sequence CRISPR CRISPR-Cas Systems Deoxyribonucleic acid DNA Evolutionary Biology Gene mapping Genes genome Genomes Human Genetics Immune system Life Sciences Metagenomics Microbial Genetics and Genomics mRNA Nucleotide sequence nucleotide sequences Nucleotides Open reading frames Plant Genetics and Genomics Position-Specific Scoring Matrices RNA Species Specificity
ISSN:	1474-760X, 1474-7596, 1474-760X
Online-Zugang:	Volltext
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