PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems

Background The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR-Cas biology, including target requirements such as the protos...

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Bibliographic Details
Published in:	Genome Biology Vol. 22; no. 1; p. 281
Main Authors:	Vink, Jochem N. A., Baijens, Jan H. L., Brouns, Stan J. J.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 30.09.2021 Springer Nature B.V BMC
Subjects:	Adaptation Animal Genetics and Genomics Bacteria Base Sequence Bioinformatics Biomedical and Life Sciences Clustered Regularly Interspaced Short Palindromic Repeats Conserved Sequence CRISPR CRISPR-Cas Systems Deoxyribonucleic acid DNA Evolutionary Biology Gene mapping Genes genome Genomes Human Genetics Immune system Life Sciences Metagenomics Microbial Genetics and Genomics mRNA Nucleotide sequence nucleotide sequences Nucleotides Open reading frames Plant Genetics and Genomics Position-Specific Scoring Matrices RNA Species Specificity
ISSN:	1474-760X, 1474-7596, 1474-760X
Online Access:	Get full text
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