LongGF: computational algorithm and software tool for fast and accurate detection of gene fusions by long-read transcriptome sequencing

Background Long-read RNA-Seq techniques can generate reads that encompass a large proportion or the entire mRNA/cDNA molecules, so they are expected to address inherited limitations of short-read RNA-Seq techniques that typically generate < 150 bp reads. However, there is a general lack of softwa...

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Bibliographic Details
Published in:	BMC genomics Vol. 21; no. Suppl 11; pp. 793 - 12
Main Authors:	Liu, Qian, Hu, Yu, Stucky, Andres, Fang, Li, Zhong, Jiang F., Wang, Kai
Format:	Journal Article
Language:	English
Published:	London BioMed Central 29.12.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Acute myeloid leukemia Algorithms Animal Genetics and Genomics Biomedical and Life Sciences Breast cancer Cancer Computational biology Computational tool Computer applications Computer programs Cytogenetics Datasets Gene expression Gene Fusion Gene sequencing Genes Genomes Genomics High-Throughput Nucleotide Sequencing Identification and classification Leukemia Life Sciences Long-read sequencing Methods Microarrays Microbial Genetics and Genomics Myeloid leukemia Ovarian cancer Plant Genetics and Genomics Porosity Proteomics Ribonucleic acid RNA RNA sequencing Sarcoma Sequence Analysis, RNA Software Software development tools Transcriptome Transcriptome sequencing Transcriptomes Translocation Tumor cell lines United States Long-read sequencing Transcriptome sequencing Computational tool Gene fusion
ISSN:	1471-2164, 1471-2164
Online Access:	Get full text
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