Novel approach based on one-tube nested PCR and a lateral flow strip for highly sensitive diagnosis of tuberculous meningitis

Rapid and sensitive detection of Mycobacterium tuberculosis (M. Tb) in cerebrospinal fluid is crucial in the diagnosis of tuberculous meningitis (TBM), but conventional diagnostic technologies have limited sensitivity and specificity or are time-consuming. In this work, a novel, highly sensitive mol...

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Vydané v:	PloS one Ročník 12; číslo 10; s. e0186985
Hlavní autori:	Sun, Yajuan, Chen, Jiajun, Li, Jia, Xu, Yawei, Jin, Hui, Xu, Na, Yin, Rui, Hu, Guohua
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Public Library of Science 30.10.2017 Public Library of Science (PLoS)
Predmet:	Biology and Life Sciences Complications and side effects Diagnosis Genetic aspects Humans Medicine and Health Sciences Meningitis Polymerase chain reaction Polymerase Chain Reaction - methods Research and Analysis Methods Risk factors Sensitivity and Specificity Tuberculosis Tuberculosis, Meningeal - diagnosis China
ISSN:	1932-6203, 1932-6203
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