Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis

Osteoarthritis (OA) is a chronic and slowly progressive disease for which biomarkers may be able to provide a more rapid indication of therapeutic responses to therapy than is currently available; this could accelerate and facilitate OA drug discovery and development programs. The goal of this docum...

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Bibliographic Details
Published in:	Osteoarthritis and cartilage Vol. 19; no. 5; pp. 515 - 542
Main Authors:	Kraus, V.B., Burnett, B., Coindreau, J., Cottrell, S., Eyre, D., Gendreau, M., Gardiner, J., Garnero, P., Hardin, J., Henrotin, Y., Heinegård, D., Ko, A., Lohmander, L.S., Matthews, G., Menetski, J., Moskowitz, R., Persiani, S., Poole, A.R., Rousseau, J.-C., Todman, M.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 2011 W.B. Saunders
Subjects:	Biological Markers/metabolism Biomarkers Biomarkers - metabolism Clinical Medicine Clinical trial Clinical Trials as Topic - methods Drug Discovery - methods Drug Monitoring - methods Human health sciences Humans Klinisk medicin Medical and Health Sciences Medicin och hälsovetenskap Osteoarthritis Osteoarthritis - diagnosis Osteoarthritis - drug therapy Osteoarthritis/diagnosis/drug therapy Rheumatology Rhumatologie Sciences de la santé humaine Specimen Handling - methods Treatment Outcome Biomarkers Clinical trial Osteoarthritis
ISSN:	1063-4584, 1522-9653, 1522-9653
Online Access:	Get full text
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