Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle
Background Domestication of the now-extinct wild aurochs, Bos primigenius , gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus . While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important q...
Gespeichert in:
| Veröffentlicht in: | Genome Biology Jg. 16; H. 1; S. 234 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
London
BioMed Central
26.10.2015
Springer Nature B.V |
| Schlagworte: | |
| ISSN: | 1474-760X, 1474-7596, 1474-760X |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Background
Domestication of the now-extinct wild aurochs,
Bos primigenius
, gave rise to the two major domestic extant cattle taxa,
B. taurus
and
B. indicus
. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.
Results
Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic
B. taurus
lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in
B. taurus
are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle.
Conclusions
This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought. |
|---|---|
| AbstractList | Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals. Results Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle. Conclusions This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought. Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.BACKGROUNDDomestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle.RESULTSPhylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle.This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought.CONCLUSIONSThis work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought. Background Domestication of the now-extinct wild aurochs, Bos primigenius , gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus . While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals. Results Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle. Conclusions This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought. Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals. Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle. This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought. |
| ArticleNumber | 234 |
| Author | MacHugh, David E. Donoghue, Mark T. Murphy, Alison Lohan, Amanda J. Tai, Shuaishuai Bradley, Daniel G. Braud, Martin Schroeder, Steven Liu, Yuan Spillane, Charles Teasdale, Matthew D. Rue-Albrecht, Kévin Magee, David A. Park, Stephen D E Edwards, Ceiridwen J. Sonstegard, Tad S. Loftus, Brendan J. McGettigan, Paul A. Chamberlain, Andrew T. |
| Author_xml | – sequence: 1 givenname: Stephen D E surname: Park fullname: Park, Stephen D E organization: IdentiGEN Ltd, Unit 2, Trinity Enterprise Centre – sequence: 2 givenname: David A. surname: Magee fullname: Magee, David A. organization: Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, Department of Animal Science, University of Connecticut – sequence: 3 givenname: Paul A. surname: McGettigan fullname: McGettigan, Paul A. organization: Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin – sequence: 4 givenname: Matthew D. surname: Teasdale fullname: Teasdale, Matthew D. organization: Smurfit Institute of Genetics, Trinity College – sequence: 5 givenname: Ceiridwen J. surname: Edwards fullname: Edwards, Ceiridwen J. organization: Research Laboratory for Archaeology and the History of Art, Dyson Perrins Building – sequence: 6 givenname: Amanda J. surname: Lohan fullname: Lohan, Amanda J. organization: UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin – sequence: 7 givenname: Alison surname: Murphy fullname: Murphy, Alison organization: UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin – sequence: 8 givenname: Martin surname: Braud fullname: Braud, Martin organization: Genetics and Biotechnology Laboratory, Plant and AgriBiosciences Research Centre (PABC), School of Natural Sciences, National University of Ireland Galway – sequence: 9 givenname: Mark T. surname: Donoghue fullname: Donoghue, Mark T. organization: Genetics and Biotechnology Laboratory, Plant and AgriBiosciences Research Centre (PABC), School of Natural Sciences, National University of Ireland Galway – sequence: 10 givenname: Yuan surname: Liu fullname: Liu, Yuan organization: BGI Shenzhen, Beishan Industrial Zone – sequence: 11 givenname: Andrew T. surname: Chamberlain fullname: Chamberlain, Andrew T. organization: Faculty of Life Sciences, University of Manchester – sequence: 12 givenname: Kévin surname: Rue-Albrecht fullname: Rue-Albrecht, Kévin organization: Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin – sequence: 13 givenname: Steven surname: Schroeder fullname: Schroeder, Steven organization: Animal Genomics and Improvement Laboratory, Agricultural Research Service, USDA – sequence: 14 givenname: Charles surname: Spillane fullname: Spillane, Charles organization: Genetics and Biotechnology Laboratory, Plant and AgriBiosciences Research Centre (PABC), School of Natural Sciences, National University of Ireland Galway – sequence: 15 givenname: Shuaishuai surname: Tai fullname: Tai, Shuaishuai organization: BGI Shenzhen, Beishan Industrial Zone – sequence: 16 givenname: Daniel G. surname: Bradley fullname: Bradley, Daniel G. organization: Smurfit Institute of Genetics, Trinity College – sequence: 17 givenname: Tad S. surname: Sonstegard fullname: Sonstegard, Tad S. organization: Animal Genomics and Improvement Laboratory, Agricultural Research Service, USDA, Recombinetics Inc – sequence: 18 givenname: Brendan J. surname: Loftus fullname: Loftus, Brendan J. organization: UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, UCD School of Medicine, University College Dublin – sequence: 19 givenname: David E. surname: MacHugh fullname: MacHugh, David E. email: david.machugh@ucd.ie organization: Animal Genomics Laboratory, UCD School of Agriculture and Food Science, University College Dublin, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26498365$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFUk1v1TAQjFAR_YAfwAVZ4sKBgO049vMFCarSIlXiAhI3a5-zyXPl2A_bKfTEXyfhtbRUAk5e2TOzu-M5rPZCDFhVTxl9xdhKvs6soa2uKWtrqjSt-YPqgAklaiXpl7079X51mPMFpUwLLh9V-1wKvWpke1D9OMUQRyQZv04YrAsDiT0pGyT4vbhgCzmZEmQHgXxzviMwpWg3-SV5FzPZJje6AYOb5gvn_TS6AAXzL_52c-XjgHFIMJcEQkfwMvqpuBiWHhZK8fi4etiDz_jk-jyqPr8_-XR8Vp9_PP1w_Pa8toqKUrc9rLWyvG-p6C1vtOpB9YIBbzoE0VBGeQsasGvVSrYWG2X7dcOU4BZgzZuj6s1OdzutR-wshpLAm2UDSFcmgjN_vgS3MUO8NEJyKls2C7y4FkhxtioXM7ps0XsIGKdsOKW0UYIx_V8oU1xpzYRczdDn96AXcUphdsJwTlUrteSL4LO7w_-e-uYbZ4DaAWyKOSfsjXUFFqfnXZw3jJolMGYXGDMHxiyBMYsv7B7zRvxfHL7j5BkbBky3Q_-d9BNhmNUo |
| CitedBy_id | crossref_primary_10_1093_molbev_msad257 crossref_primary_10_1016_j_ympev_2018_09_015 crossref_primary_10_1080_14614103_2018_1536498 crossref_primary_10_1126_science_aba9572 crossref_primary_10_1038_hdy_2016_79 crossref_primary_10_7554_eLife_93076 crossref_primary_10_1016_j_jasrep_2022_103589 crossref_primary_10_1186_s12864_020_07270_x crossref_primary_10_1073_pnas_1606340113 crossref_primary_10_3390_ani11102833 crossref_primary_10_1111_zsc_12212 crossref_primary_10_1038_s41598_020_66272_7 crossref_primary_10_1111_jbi_15086 crossref_primary_10_1186_s12864_019_5685_2 crossref_primary_10_1093_molbev_msae076 crossref_primary_10_1111_age_13104 crossref_primary_10_1186_s12711_017_0349_7 crossref_primary_10_1186_s12864_022_08561_1 crossref_primary_10_1016_j_jas_2016_08_008 crossref_primary_10_1007_s00251_021_01211_y crossref_primary_10_1093_jmammal_gyy184 crossref_primary_10_1038_s41467_018_04737_0 crossref_primary_10_1093_molbev_msw184 crossref_primary_10_1016_j_ygeno_2022_110448 crossref_primary_10_1111_1365_2435_12843 crossref_primary_10_3389_fgene_2018_00051 crossref_primary_10_3390_genes15040509 crossref_primary_10_3389_fevo_2020_00103 crossref_primary_10_1007_s00334_016_0597_4 crossref_primary_10_1186_s13059_015_0793_z crossref_primary_10_1038_s41467_022_30097_x crossref_primary_10_1073_pnas_1901169116 crossref_primary_10_1111_mec_13556 crossref_primary_10_1016_j_quaint_2017_02_009 crossref_primary_10_7717_peerj_6399 crossref_primary_10_1186_s12864_021_07412_9 crossref_primary_10_1111_cobi_13867 crossref_primary_10_1016_j_jas_2020_105321 crossref_primary_10_1038_s41586_024_08112_6 crossref_primary_10_1111_eva_12674 crossref_primary_10_1038_s41576_018_0082_2 crossref_primary_10_1111_age_12408 crossref_primary_10_1038_s41467_020_15848_y crossref_primary_10_1038_s41588_018_0056_5 crossref_primary_10_1126_science_aas9411 crossref_primary_10_1038_s41598_018_34243_8 crossref_primary_10_1038_s41598_025_86887_y crossref_primary_10_3390_genes10070509 crossref_primary_10_1002_ece3_3699 crossref_primary_10_1007_s00438_017_1339_8 crossref_primary_10_1016_j_scib_2024_09_016 crossref_primary_10_1038_s42003_021_02874_9 crossref_primary_10_1016_j_ygeno_2019_02_004 crossref_primary_10_1016_j_chom_2020_01_008 crossref_primary_10_1038_s41598_017_17127_1 crossref_primary_10_1371_journal_pone_0249537 crossref_primary_10_1186_s40850_024_00195_y crossref_primary_10_3390_genes11080932 crossref_primary_10_1016_j_jas_2018_09_001 crossref_primary_10_1080_03014460_2021_1942205 crossref_primary_10_1098_rsos_160107 crossref_primary_10_1002_ece3_4550 crossref_primary_10_1177_14696053211055475 crossref_primary_10_3390_d14110895 crossref_primary_10_3389_fgene_2023_1099896 crossref_primary_10_1186_s12864_017_3883_3 crossref_primary_10_1146_annurev_animal_022516_022747 crossref_primary_10_1111_age_12974 crossref_primary_10_1093_molbev_msw254 crossref_primary_10_1186_s12859_017_1613_0 crossref_primary_10_1186_s12915_019_0724_7 crossref_primary_10_1016_j_cub_2023_08_031 crossref_primary_10_1111_eva_12770 crossref_primary_10_3390_d13080370 crossref_primary_10_3390_genes14010234 crossref_primary_10_1186_s13059_019_1627_1 crossref_primary_10_1371_journal_pgen_1007191 crossref_primary_10_1111_mec_17566 crossref_primary_10_3390_d10030065 crossref_primary_10_1093_nar_gkx361 crossref_primary_10_5334_oq_25 crossref_primary_10_3390_agriculture12122059 crossref_primary_10_3389_fgene_2017_00108 crossref_primary_10_1073_pnas_1519508113 crossref_primary_10_1093_gigascience_gix049 crossref_primary_10_1038_s41467_018_03206_y crossref_primary_10_1016_j_mgene_2018_06_015 crossref_primary_10_1186_s12711_021_00639_w crossref_primary_10_3389_fmicb_2016_00503 crossref_primary_10_1038_nrg_2017_65 crossref_primary_10_1016_j_jas_2019_104993 crossref_primary_10_1038_s41576_020_0225_0 crossref_primary_10_1371_journal_pone_0278681 crossref_primary_10_1007_s44154_023_00085_2 crossref_primary_10_1371_journal_pone_0175916 crossref_primary_10_3390_agriculture13122255 crossref_primary_10_3390_ani12182401 crossref_primary_10_3390_genes16060639 crossref_primary_10_1016_j_ejbt_2016_07_001 crossref_primary_10_1038_srep31279 crossref_primary_10_1002_ece3_7056 crossref_primary_10_1016_j_jasrep_2017_04_022 crossref_primary_10_1534_genetics_116_194860 crossref_primary_10_3390_genes9070367 crossref_primary_10_1111_mec_15004 crossref_primary_10_3390_ani14040645 crossref_primary_10_1038_s41598_018_36444_7 crossref_primary_10_2989_10220119_2021_1886434 crossref_primary_10_1038_s42003_018_0176_6 crossref_primary_10_1093_biolre_iox004 crossref_primary_10_1093_sysbio_syw059 crossref_primary_10_1101_gr_277481_122 crossref_primary_10_7554_eLife_93076_3 crossref_primary_10_1007_s00251_020_01197_z crossref_primary_10_3389_fgene_2017_00003 crossref_primary_10_1126_science_aav1002 crossref_primary_10_1002_jez_b_23105 crossref_primary_10_1093_molbev_msw129 crossref_primary_10_1111_1365_2435_12705 |
| Cites_doi | 10.1371/journal.pone.0005350 10.1038/nature08365 10.1038/ng.3034 10.1038/ncomms6257 10.1073/pnas.1303367110 10.1038/ncomms3755 10.1093/nar/29.23.4793 10.1038/srep05559 10.1371/journal.pone.0038601 10.1038/nature12323 10.1371/journal.pgen.1002967 10.1111/j.2517-6161.1995.tb02031.x 10.1073/pnas.91.7.2757 10.1007/s00251-012-0671-8 10.1126/science.1167936 10.1371/journal.pone.0034131 10.1016/j.crvi.2010.12.009 10.1038/35074088 10.3390/d6010178 10.1073/pnas.1416991111 10.1371/journal.pgen.0020190 10.1093/bioinformatics/btp324 10.1371/journal.pone.0009255 10.1371/journal.pone.0005753 10.1016/j.metabol.2009.10.022 10.1093/bioinformatics/btt193 10.1073/pnas.0308518100 10.1016/j.cub.2008.01.019 10.1038/nature11622 10.1182/blood-2004-06-2344 10.1186/gb-2009-10-4-r42 10.1038/nature12736 10.1371/journal.pone.0078575 10.1016/j.cell.2004.12.035 10.1021/bi9010557 10.1371/journal.pgen.1004148 10.1073/pnas.1412627111 10.1371/journal.pone.0015922 10.1038/nature01019 10.1371/journal.pgen.1004254 10.1038/hdy.2009.68 10.1126/science.1188021 10.1038/hdy.2010.30 10.1098/rspb.2007.0020 10.1186/gb-2011-12-11-r112 10.1073/pnas.142293799 10.1038/nature13025 10.1093/sysbio/syq010 10.1098/rsbl.2008.0342 10.1073/pnas.1114546109 10.1126/science.1224344 10.1093/molbev/msr048 10.1186/1471-2164-14-148 10.1186/1471-2164-15-162 10.1093/genetics/146.3.1071 10.1126/science.1169588 10.1093/bioinformatics/btq330 10.1186/1471-2105-11-133 10.1111/j.1365-294X.2012.05664.x 10.1007/s00335-013-9464-0 10.1038/ng.806 10.1038/nature12886 10.1098/rspb.2005.3243 10.1038/emboj.2009.222 10.1093/genetics/155.2.945 10.1073/pnas.96.16.9045 10.1111/j.1365-2052.2012.02328.x 10.1371/journal.pone.0003418 10.1101/gr.163592.113 10.1038/nature08832 10.1093/molbev/mss153 10.1101/gr.224202 10.1371/journal.pgen.1002316 10.1017/S0003598X00047864 10.1038/srep05798 10.1073/pnas.1410083111 10.1073/pnas.86.6.1939 10.1111/j.1365-2052.1994.tb00440.x 10.1371/journal.pone.0014782 10.1046/j.1471-8286.2003.00566.x 10.1038/ng.2811 10.1093/genetics/116.1.153 10.1371/journal.pone.0015760 10.1016/j.cub.2015.04.007 10.1186/1471-2164-10-550 |
| ContentType | Journal Article |
| Copyright | Park et al. 2015 2015. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: Park et al. 2015 – notice: 2015. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M7P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS 7X8 7S9 L.6 5PM |
| DOI | 10.1186/s13059-015-0790-2 |
| DatabaseName | Springer Nature OA Free Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection (ProQuest) ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest SciTech Collection ProQuest Natural Science Collection ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials - QC Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central Proquest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Collection (ProQuest) ProQuest Health & Medical Complete (Alumni) Biological Sciences ProQuest Health & Medical Collection Medical Database Biological Science Database Proquest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic AGRICOLA AGRICOLA - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | Publicly Available Content Database AGRICOLA MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1474-760X |
| EndPage | 234 |
| ExternalDocumentID | PMC4620651 26498365 10_1186_s13059_015_0790_2 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | England Europe United Kingdom--UK United Kingdom |
| GeographicLocations_xml | – name: England – name: Europe – name: United Kingdom--UK – name: United Kingdom |
| GrantInformation_xml | – fundername: European Research Council grantid: 295729-CodeX funderid: http://dx.doi.org/10.13039/501100000781 – fundername: Department of Agriculture, Food and the Marine grantid: RSF 06 406 funderid: http://dx.doi.org/10.13039/501100001584 – fundername: Science Foundation Ireland grantid: SFI/08/IN.1/B2038 – fundername: Wellcome Trust grantid: 097429/Z/11/Z funderid: http://dx.doi.org/10.13039/100004440 – fundername: Seventh Framework Programme grantid: KBBE-211602- MACROSYS funderid: http://dx.doi.org/10.13039/501100004963 – fundername: Wellcome Trust |
| GroupedDBID | --- 0R~ 29H 4.4 53G 5GY 5VS 7X7 88E 8FE 8FH 8FI 8FJ AAFWJ AAHBH AAJSJ AASML ABUWG ACGFO ACGFS ACJQM ACPRK ADBBV ADUKV AEGXH AFKRA AFPKN AHBYD AHSBF AIAGR ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIAM AOIJS BAPOH BAWUL BBNVY BCNDV BENPR BFQNJ BHPHI BMC BPHCQ BVXVI C6C CCPQU EBD EBLON EBS EMOBN FYUFA GROUPED_DOAJ GX1 HCIFZ HMCUK HYE IAO IGS IHR ISR ITC KPI LK8 M1P M7P PHGZM PHGZT PIMPY PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PUEGO ROL RPM RSV SJN SOJ SV3 UKHRP AAYXX AFFHD CITATION 3V. ACRMQ ADINQ ALIPV C24 CGR CUY CVF ECM EIF NPM 7XB 8FK AZQEC DWQXO GNUQQ K9. PKEHL PQEST PQUKI PRINS 7X8 7S9 L.6 5PM |
| ID | FETCH-LOGICAL-c704t-5fab97c2f504fc2397fa7f41a23dea4301025a9aed57865ce37cfb31742caab23 |
| IEDL.DBID | M7P |
| ISICitedReferencesCount | 136 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000363385700001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1474-760X 1474-7596 |
| IngestDate | Tue Nov 04 01:59:25 EST 2025 Fri Sep 05 09:35:53 EDT 2025 Sun Nov 09 12:39:55 EST 2025 Tue Oct 14 12:41:04 EDT 2025 Thu Jan 02 22:52:24 EST 2025 Sat Nov 29 04:55:45 EST 2025 Tue Nov 18 21:26:58 EST 2025 Sat Sep 06 07:24:41 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Ancient DNA Cattle Domestication Evolution Aurochs Hybridization Genome |
| Language | English |
| License | Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c704t-5fab97c2f504fc2397fa7f41a23dea4301025a9aed57865ce37cfb31742caab23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.proquest.com/docview/2207569629?pq-origsite=%requestingapplication% |
| PMID | 26498365 |
| PQID | 2207569629 |
| PQPubID | 2040232 |
| PageCount | 1 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_4620651 proquest_miscellaneous_2000374119 proquest_miscellaneous_1727991468 proquest_journals_2207569629 pubmed_primary_26498365 crossref_citationtrail_10_1186_s13059_015_0790_2 crossref_primary_10_1186_s13059_015_0790_2 springer_journals_10_1186_s13059_015_0790_2 |
| PublicationCentury | 2000 |
| PublicationDate | 2015-10-26 |
| PublicationDateYYYYMMDD | 2015-10-26 |
| PublicationDate_xml | – month: 10 year: 2015 text: 2015-10-26 day: 26 |
| PublicationDecade | 2010 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England |
| PublicationTitle | Genome Biology |
| PublicationTitleAbbrev | Genome Biol |
| PublicationTitleAlternate | Genome Biol |
| PublicationYear | 2015 |
| Publisher | BioMed Central Springer Nature B.V |
| Publisher_xml | – name: BioMed Central – name: Springer Nature B.V |
| References | E Palkopoulou (790_CR42) 2015; 25 S Sawyer (790_CR30) 2012; 7 S Bonfiglio (790_CR56) 2012; 43 L Orlando (790_CR24) 2013; 499 CJ Stevens (790_CR27) 2012; 86 S Guindon (790_CR49) 2010; 59 DM Larkin (790_CR21) 2012; 109 L Perez-Pardal (790_CR58) 2010; 105 A Achilli (790_CR12) 2009; 4 M Schubert (790_CR22) 2014; 111 J Clutton-Brock (790_CR3) 1990 BP Lewis (790_CR91) 2005; 120 DE MacHugh (790_CR7) 1997; 146 S Koks (790_CR46) 2013; 24 HD Daetwyler (790_CR19) 2014; 46 MA Groenen (790_CR23) 2012; 491 CG Elsik (790_CR37) 2009; 324 A Achilli (790_CR13) 2008; 18 RT Loftus (790_CR6) 1994; 91 J Diamond (790_CR72) 2002; 418 DP Toews (790_CR18) 2012; 21 J Lenstra (790_CR54) 2014; 6 AV Zimin (790_CR29) 2009; 10 CS Troy (790_CR8) 2001; 410 CJ Rubin (790_CR26) 2010; 464 CM Leu (790_CR77) 2005; 105 JE Decker (790_CR20) 2014; 10 B Grisart (790_CR68) 2004; 101 C Glaser (790_CR76) 2010; 59 NA Rosenberg (790_CR84) 2004; 4 JD Vigne (790_CR1) 2011; 334 CJ Edwards (790_CR10) 2010; 5 M Hofreiter (790_CR31) 2001; 29 S Paabo (790_CR39) 1989; 86 A Seguin-Orlando (790_CR45) 2013; 8 O Smith (790_CR43) 2014; 4 AE Minoche (790_CR36) 2011; 12 M Li (790_CR65) 2013; 45 MJ Montague (790_CR66) 2014; 111 N Murakami (790_CR75) 2009; 48 RR Hudson (790_CR70) 1987; 116 A Esteve-Codina (790_CR89) 2013; 14 JA Guerra-Assuncao (790_CR90) 2010; 11 JS Pedersen (790_CR40) 2014; 24 RE Green (790_CR87) 2010; 328 RH Meadow (790_CR2) 1993 MA Greagg (790_CR41) 1999; 96 A Winter (790_CR69) 2002; 99 H Jonsson (790_CR83) 2013; 29 RA Gibbs (790_CR5) 2009; 324 RE Green (790_CR38) 2009; 28 A Vaysse (790_CR73) 2011; 7 S Bonfiglio (790_CR55) 2012; 7 790_CR78 Y Benjamini (790_CR71) 1995; 57 H Zhang (790_CR53) 2013; 4 TH Lee (790_CR48) 2014; 15 H Li (790_CR79) 2009; 25 S Qanbari (790_CR25) 2014; 10 C Gamba (790_CR44) 2014; 5 DG Bradley (790_CR4) 1994; 25 S Bonfiglio (790_CR14) 2010; 5 JK Pritchard (790_CR51) 2000; 155 EY Durand (790_CR59) 2011; 28 H Jonsson (790_CR64) 2014; 111 D Reich (790_CR61) 2009; 461 KA Moutou (790_CR74) 2013; 65 M Raghavan (790_CR34) 2014; 505 790_CR85 790_CR82 N Patterson (790_CR86) 2006; 2 790_CR81 M Gautier (790_CR88) 2009; 10 W McLaren (790_CR47) 2010; 26 K Prufer (790_CR33) 2014; 505 AJ Amaral (790_CR62) 2011; 6 M Meyer (790_CR32) 2012; 338 LK Matukumalli (790_CR50) 2009; 4 MA DePristo (790_CR80) 2011; 43 CJ Edwards (790_CR28) 2007; 274 JK Pickrell (790_CR60) 2012; 8 A Gotherstrom (790_CR16) 2005; 272 EJ McTavish (790_CR52) 2013; 110 CJ Edwards (790_CR11) 2011; 6 J Schibler (790_CR9) 2014; 4 R Bollongino (790_CR15) 2008; 3 R Chen (790_CR63) 2012; 29 E Svensson (790_CR17) 2008; 4 J Kantanen (790_CR57) 2009; 103 M Rasmussen (790_CR35) 2014; 506 B Grisart (790_CR67) 2002; 12 26498490 - Genome Biol. 2015;16:225 |
| References_xml | – volume: 4 year: 2009 ident: 790_CR50 publication-title: PLoS One doi: 10.1371/journal.pone.0005350 – volume: 461 start-page: 489 year: 2009 ident: 790_CR61 publication-title: Nature doi: 10.1038/nature08365 – volume: 46 start-page: 858 year: 2014 ident: 790_CR19 publication-title: Nat Genet doi: 10.1038/ng.3034 – volume: 5 start-page: 5257 year: 2014 ident: 790_CR44 publication-title: Nat Commun doi: 10.1038/ncomms6257 – volume: 110 start-page: E1398 year: 2013 ident: 790_CR52 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1303367110 – volume: 4 start-page: 2755 year: 2013 ident: 790_CR53 publication-title: Nat Commun doi: 10.1038/ncomms3755 – volume: 29 start-page: 4793 year: 2001 ident: 790_CR31 publication-title: Nucleic Acids Res doi: 10.1093/nar/29.23.4793 – volume: 4 start-page: 5559 year: 2014 ident: 790_CR43 publication-title: Sci Rep doi: 10.1038/srep05559 – volume: 7 year: 2012 ident: 790_CR55 publication-title: PLoS One doi: 10.1371/journal.pone.0038601 – volume: 499 start-page: 74 year: 2013 ident: 790_CR24 publication-title: Nature doi: 10.1038/nature12323 – volume: 8 year: 2012 ident: 790_CR60 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1002967 – volume: 57 start-page: 289 year: 1995 ident: 790_CR71 publication-title: J R Stat Soc Ser B Method doi: 10.1111/j.2517-6161.1995.tb02031.x – volume: 91 start-page: 2757 year: 1994 ident: 790_CR6 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.91.7.2757 – volume: 65 start-page: 195 year: 2013 ident: 790_CR74 publication-title: Immunogenetics doi: 10.1007/s00251-012-0671-8 – volume: 324 start-page: 528 year: 2009 ident: 790_CR5 publication-title: Science doi: 10.1126/science.1167936 – volume: 7 year: 2012 ident: 790_CR30 publication-title: PLoS One doi: 10.1371/journal.pone.0034131 – volume: 334 start-page: 171 year: 2011 ident: 790_CR1 publication-title: C R Biol doi: 10.1016/j.crvi.2010.12.009 – volume: 410 start-page: 1088 year: 2001 ident: 790_CR8 publication-title: Nature doi: 10.1038/35074088 – volume: 6 start-page: 178 year: 2014 ident: 790_CR54 publication-title: Diversity doi: 10.3390/d6010178 – ident: 790_CR78 – volume: 111 start-page: E5661 year: 2014 ident: 790_CR22 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1416991111 – volume: 2 year: 2006 ident: 790_CR86 publication-title: PLoS Genet doi: 10.1371/journal.pgen.0020190 – volume: 25 start-page: 1754 year: 2009 ident: 790_CR79 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btp324 – volume: 5 year: 2010 ident: 790_CR10 publication-title: PLoS One doi: 10.1371/journal.pone.0009255 – volume: 4 year: 2009 ident: 790_CR12 publication-title: PLoS One doi: 10.1371/journal.pone.0005753 – volume: 59 start-page: 993 year: 2010 ident: 790_CR76 publication-title: Metabolism doi: 10.1016/j.metabol.2009.10.022 – volume: 29 start-page: 1682 year: 2013 ident: 790_CR83 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btt193 – volume: 101 start-page: 2398 year: 2004 ident: 790_CR68 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0308518100 – volume: 18 start-page: R157 year: 2008 ident: 790_CR13 publication-title: Curr Biol doi: 10.1016/j.cub.2008.01.019 – volume: 491 start-page: 393 year: 2012 ident: 790_CR23 publication-title: Nature doi: 10.1038/nature11622 – volume: 105 start-page: 1121 year: 2005 ident: 790_CR77 publication-title: Blood doi: 10.1182/blood-2004-06-2344 – volume: 10 start-page: R42 year: 2009 ident: 790_CR29 publication-title: Genome Biol doi: 10.1186/gb-2009-10-4-r42 – volume: 505 start-page: 87 year: 2014 ident: 790_CR34 publication-title: Nature doi: 10.1038/nature12736 – volume: 8 year: 2013 ident: 790_CR45 publication-title: PLoS One doi: 10.1371/journal.pone.0078575 – volume: 120 start-page: 15 year: 2005 ident: 790_CR91 publication-title: Cell doi: 10.1016/j.cell.2004.12.035 – volume: 48 start-page: 9297 year: 2009 ident: 790_CR75 publication-title: Biochemistry doi: 10.1021/bi9010557 – volume-title: The walking larder: patterns of domestication, pastoralism, and predation (one world archaeology) year: 1990 ident: 790_CR3 – volume: 10 year: 2014 ident: 790_CR25 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1004148 – start-page: 295 volume-title: Harappan civilization: a recent perspective. 2. rev. edition year: 1993 ident: 790_CR2 – volume: 111 start-page: 18655 year: 2014 ident: 790_CR64 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1412627111 – volume: 6 year: 2011 ident: 790_CR11 publication-title: PLoS One doi: 10.1371/journal.pone.0015922 – volume: 418 start-page: 700 year: 2002 ident: 790_CR72 publication-title: Nature doi: 10.1038/nature01019 – ident: 790_CR82 – volume: 10 year: 2014 ident: 790_CR20 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1004254 – volume: 103 start-page: 404 year: 2009 ident: 790_CR57 publication-title: Heredity (Edinb) doi: 10.1038/hdy.2009.68 – volume: 328 start-page: 710 year: 2010 ident: 790_CR87 publication-title: Science doi: 10.1126/science.1188021 – volume: 105 start-page: 511 year: 2010 ident: 790_CR58 publication-title: Heredity (Edinb) doi: 10.1038/hdy.2010.30 – volume: 274 start-page: 1377 year: 2007 ident: 790_CR28 publication-title: Proc Biol Sci doi: 10.1098/rspb.2007.0020 – volume: 12 start-page: R112 year: 2011 ident: 790_CR36 publication-title: Genome Biol doi: 10.1186/gb-2011-12-11-r112 – volume: 99 start-page: 9300 year: 2002 ident: 790_CR69 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.142293799 – volume: 506 start-page: 225 year: 2014 ident: 790_CR35 publication-title: Nature doi: 10.1038/nature13025 – volume: 59 start-page: 307 year: 2010 ident: 790_CR49 publication-title: Syst Biol doi: 10.1093/sysbio/syq010 – volume: 4 start-page: 752 year: 2008 ident: 790_CR17 publication-title: Biol Lett doi: 10.1098/rsbl.2008.0342 – volume: 109 start-page: 7693 year: 2012 ident: 790_CR21 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1114546109 – volume: 338 start-page: 222 year: 2012 ident: 790_CR32 publication-title: Science doi: 10.1126/science.1224344 – volume: 28 start-page: 2239 year: 2011 ident: 790_CR59 publication-title: Mol Biol Evol doi: 10.1093/molbev/msr048 – volume: 14 start-page: 148 year: 2013 ident: 790_CR89 publication-title: BMC Genomics doi: 10.1186/1471-2164-14-148 – volume: 15 start-page: 162 year: 2014 ident: 790_CR48 publication-title: BMC Genomics doi: 10.1186/1471-2164-15-162 – volume: 146 start-page: 1071 year: 1997 ident: 790_CR7 publication-title: Genetics doi: 10.1093/genetics/146.3.1071 – volume: 324 start-page: 522 year: 2009 ident: 790_CR37 publication-title: Science doi: 10.1126/science.1169588 – volume: 26 start-page: 2069 year: 2010 ident: 790_CR47 publication-title: Bioinformatics doi: 10.1093/bioinformatics/btq330 – ident: 790_CR81 – volume: 11 start-page: 133 year: 2010 ident: 790_CR90 publication-title: BMC Bioinformatics doi: 10.1186/1471-2105-11-133 – volume: 21 start-page: 3907 year: 2012 ident: 790_CR18 publication-title: Mol Ecol doi: 10.1111/j.1365-294X.2012.05664.x – volume: 24 start-page: 309 year: 2013 ident: 790_CR46 publication-title: Mamm Genome doi: 10.1007/s00335-013-9464-0 – volume: 43 start-page: 491 year: 2011 ident: 790_CR80 publication-title: Nat Genet doi: 10.1038/ng.806 – ident: 790_CR85 – volume: 505 start-page: 43 year: 2014 ident: 790_CR33 publication-title: Nature doi: 10.1038/nature12886 – volume: 272 start-page: 2345 year: 2005 ident: 790_CR16 publication-title: Proc Biol Sci doi: 10.1098/rspb.2005.3243 – volume: 28 start-page: 2494 year: 2009 ident: 790_CR38 publication-title: EMBO J doi: 10.1038/emboj.2009.222 – volume: 155 start-page: 945 year: 2000 ident: 790_CR51 publication-title: Genetics doi: 10.1093/genetics/155.2.945 – volume: 96 start-page: 9045 year: 1999 ident: 790_CR41 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.96.16.9045 – volume: 43 start-page: 611 year: 2012 ident: 790_CR56 publication-title: Anim Genet doi: 10.1111/j.1365-2052.2012.02328.x – volume: 3 year: 2008 ident: 790_CR15 publication-title: PLoS One doi: 10.1371/journal.pone.0003418 – volume: 24 start-page: 454 year: 2014 ident: 790_CR40 publication-title: Genome Res doi: 10.1101/gr.163592.113 – volume: 464 start-page: 587 year: 2010 ident: 790_CR26 publication-title: Nature doi: 10.1038/nature08832 – volume: 29 start-page: 3475 year: 2012 ident: 790_CR63 publication-title: Mol Biol Evol doi: 10.1093/molbev/mss153 – volume: 12 start-page: 222 year: 2002 ident: 790_CR67 publication-title: Genome Res doi: 10.1101/gr.224202 – volume: 7 year: 2011 ident: 790_CR73 publication-title: PLoS Genet doi: 10.1371/journal.pgen.1002316 – volume: 86 start-page: 707 year: 2012 ident: 790_CR27 publication-title: Antiquity doi: 10.1017/S0003598X00047864 – volume: 4 start-page: 5798 year: 2014 ident: 790_CR9 publication-title: Sci Rep doi: 10.1038/srep05798 – volume: 111 start-page: 17230 year: 2014 ident: 790_CR66 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1410083111 – volume: 86 start-page: 1939 year: 1989 ident: 790_CR39 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.86.6.1939 – volume: 25 start-page: 7 year: 1994 ident: 790_CR4 publication-title: Anim Genet doi: 10.1111/j.1365-2052.1994.tb00440.x – volume: 6 year: 2011 ident: 790_CR62 publication-title: PLoS One doi: 10.1371/journal.pone.0014782 – volume: 4 start-page: 137 year: 2004 ident: 790_CR84 publication-title: Mol Ecol Notes doi: 10.1046/j.1471-8286.2003.00566.x – volume: 45 start-page: 1431 year: 2013 ident: 790_CR65 publication-title: Nat Genet doi: 10.1038/ng.2811 – volume: 116 start-page: 153 year: 1987 ident: 790_CR70 publication-title: Genetics doi: 10.1093/genetics/116.1.153 – volume: 5 year: 2010 ident: 790_CR14 publication-title: PLoS One doi: 10.1371/journal.pone.0015760 – volume: 25 start-page: 1395 year: 2015 ident: 790_CR42 publication-title: Curr Biol doi: 10.1016/j.cub.2015.04.007 – volume: 10 start-page: 550 year: 2009 ident: 790_CR88 publication-title: BMC Genomics doi: 10.1186/1471-2164-10-550 – reference: 26498490 - Genome Biol. 2015;16:225 |
| SSID | ssj0019426 ssj0017866 |
| Score | 2.542466 |
| Snippet | Background
Domestication of the now-extinct wild aurochs,
Bos primigenius
, gave rise to the two major domestic extant cattle taxa,
B. taurus
and
B. indicus
.... Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While... Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus.... BACKGROUND: Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus.... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 234 |
| SubjectTerms | Animal Genetics and Genomics Animal populations Animals Bioinformatics Biomedical and Life Sciences Bos primigenius Bos taurus Bos taurus indicus Bovidae Cattle Cattle - genetics Chromosomes Deoxyribonucleic acid DNA Domestication England Europe Evolution, Molecular Evolutionary Biology Evolutionary genetics Extinct species Extinction Extinction, Biological Gene flow Gene loci Genetic diversity Genetic Variation genome Genomes Genomics Human Genetics Life Sciences Metabolism Microbial Genetics and Genomics MicroRNAs Mitochondrial DNA neurophysiology Nucleotide sequence nucleotide sequences Phylogeny Phylogeography Plant Genetics and Genomics Polymorphism Positive selection Ruminants - classification Ruminants - genetics Sequence Analysis, DNA Single-nucleotide polymorphism United Kingdom |
| SummonAdditionalLinks | – databaseName: SpringerLINK Contemporary 1997-Present dbid: RSV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1db9YgFCZmauKNzq9ZnQYTr9TGllIol7psemEW48eyOwIUYhNHl7dvl-zKv74DpTWvcyZ6Ww4thfPxkAPPQehFaY3W8XYPczqnZWtzTSqdA0LSXFfMicj2efSRHx42x8fiU7rHPcyn3eeUZPTU0awb9mYAb1uHsz11XnBR5OB3r0O0a4I1fv5ytKQOBMSclL78Y7fNAHQJVV4-HPlbhjQGnoM7_zXkbXQ74Uz8dlKMu-ia9ffQzany5Pl99PO99f2JxekkNbwU9w4DGMTgrDtv1nh_XMULlhjAdIvVGEprDa_xu37Ap6EUGCheN8KDLpRK7nyArLE_LBt8wiYmbKx8i-1Z0u_wDRNZkx-gbwf7X_c-5KkWQ254Qdd57ZQW3BBXF9QZAijGKe5oqUjVWkWrQE1XB6bvFlwAq42tuHEawAklRilY_odoy_fePkKYiraCrTEIA5ShhuiK8taaOkx5AXv7DBXzAkmTiMpDvYwfMm5YGianeZUwrzLMqyQZerl0OZ1YOv4mvDuvukwGO0hCADsxwYjI0POlGUwt5E-Ut_04yID1AE5T1lwtQyZGn7KE9-xMirSMCLCnaCpWZ4hvqNgiEKi-N1t89z1SflNGACuWGXo1K9qvoV_5o4__SfoJukWCpkJcJmwXba1Xo32KbpizdTesnkUbuwCyySbN priority: 102 providerName: Springer Nature |
| Title | Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle |
| URI | https://link.springer.com/article/10.1186/s13059-015-0790-2 https://www.ncbi.nlm.nih.gov/pubmed/26498365 https://www.proquest.com/docview/2207569629 https://www.proquest.com/docview/1727991468 https://www.proquest.com/docview/2000374119 https://pubmed.ncbi.nlm.nih.gov/PMC4620651 |
| Volume | 16 |
| WOSCitedRecordID | wos000363385700001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVADU databaseName: Open Access: BioMedCentral Open Access Titles customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017866 issn: 1474-760X databaseCode: RBZ dateStart: 20000101 isFulltext: true titleUrlDefault: https://www.biomedcentral.com/search/ providerName: BioMedCentral – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: DOA dateStart: 20000101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: M7P dateStart: 20150101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: 7X7 dateStart: 20150101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: BENPR dateStart: 20150101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: PIMPY dateStart: 20150101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVAVX databaseName: SpringerLINK Contemporary 1997-Present customDbUrl: eissn: 1474-760X dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0019426 issn: 1474-760X databaseCode: RSV dateStart: 20000201 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELZoCxIX3o9AWRmJExA1cRw7OSEWbQEJVlGBauESxY4jIrXJstlU4sRfZ8bxplqq9sIlUhJnY-88_MUz_oaQF6HRStndPaJSPg9L4ysWKR8QkpIqElVq2T6PP8n5PFks0swtuHUurXLjE62jLluNa-QHjMHkJlLB0jfLXz5WjcLoqiuhsUP2kCUhsql72RhFkAliFXeScjZsNcIExDgVLsQZJuKgA0ceY9pQ7AcyDXy2PUldQJ4XEyj_iaLayenw9v8O6w655WApfTvo0V1yzTT3yI2hUOXv--TPe9O0p4a6xGvoA20rCtiRgm-vG72ms35l92NSwN4lLXqsxNW9ptO2o0usHAZ6WvdwocbKynWDCNc-D1KGVxhHnE2LpqTmzJkDvkNbkuUH5Nvh7Ou7D74r3eBrGfC1H1eFSqVmVRzwSjMAPVUhKx4WLCpNwSNksouRGLwEjyFibSKpKwVYhjNdFKAtD8lu0zbmMaE8LSP4kobGgHy4ZirisjQ6xn8_MCrySLCRVa4drzmW1zjJ7fdNIvJBvDmIN0fx5swjL8dHlgOpx1WN9zeSy519d_m52DzyfLwNlonhlqIxbd_lCA0BfXORXN6GDQRAYQi_82jQqbFHAFXTJBKxR-SWto0NkBl8-05T_7QM4VwwgJahR15t9PK865cO9MnVA31KbjK0EJi3mdgnu-tVb56R6_psXXerCdmRC2mPyYTsTWfz7Ghi1zcm1iThWvbxc_Ydzo6mP_D45fgvzSw-Ug |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB5VWxBceEMDBYwEFyBq4jhOckCIR0tX3a72UFA5hdhx1EiQLJtNUU_8I34jM3lVS9XeeuCYjZ3Em288nzPjbwCeu0Yr1ezukZmyhZsaW3FP2ciQVKA8mUWN2ueXSTCdhoeH0WwN_vR7YSitsp8Tm4k6LTV9I9_iHJ2bjCSP3s5_2lQ1iqKrfQmNFhZ75uQXLtmqN-OP-H5fcL6zffBh1-6qCtg6cMTS9rNERYHmme-ITHP0x1kSZMJNuJeaRHgksuaTZnWKYJa-Nl6gM4VuVnCdJIqEDnDKXxcI9nAE67Px_uzrELfAHnI4iARvNzdRyqMfyS6o6oZyq0LX4VOikm87QeTYfNUtnuG6Z1M2_4nbNu5w5-b_9kfeghsd8WbvWku5DWumuANX21KcJ3fh9ydTlD8M61LLccyszBiyY4beKy_0km3Xi2bHKcPVRcqSmmqNVa_Z-7Jic6qNhpaY1_hDTrWj84I4fNMfcYy3MJ00OEuKlJnjzuDpHrqRkb4Hny9l9PdhVJSF2QAmotQLXA8bI7cTmitPBKnRPr1txyjPAqfHRqw75XYqIPI9blZwoYxbOMUIp5jgFHMLXg5d5q1syUWNN3ukxN0MVsWnMLHg2XAa5x4KKCWFKesqJvKL6wshw_Pb8FbiyHXxOg9aDA9PhGQ8Cj3pWxCsoHtoQNrnq2eK_KjRQBeSI3l2LXjV28Hpo5870IcXD_QpXNs92J_Ek_F07xFc52SdyFK43ITRclGbx3BFHy_zavGkM3sG3y7bQP4CWyiVqQ |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3fb9UgFCZm_ogvzl_TuqmY-KQ2aymF9nHqrhqXmyXqsjcCFGITpTe37RKf_Nc9tLTLdc7E-NoeCoUP-E4OfAeh56nRSg23e5hVMU0rEyuSqRgYkuIqY7Yc1D5PjvhyWZyelschz2k7nXafQpLjnQav0uS6_VVlxylesP0WVt7cn_PJ44SXSQxr8FXqcwZ5d_3TyRxGKGH_CaHMPxbb3IwuMMyLByV_i5YOm9Bi-7-bfxvdCvwTH4yAuYOuGHcXXR8zUv64h36-M675bnA4YQ0V4MZiIIkYFvHa6Q4f9uvh4iUGkl1h2fuUW-0r_Lpp8cqnCANA1j08qH0K5dp5KjuUh-GEKkxQyMbSVdicBdz7OvSgpnwffVkcfn7zPg45GmLNE9rFuZWq5JrYPKFWE2A3VnJLU0myykiaecm63CuAV7A0sFybjGurgLRQoqUEWOygLdc48xBhWlYZuMxgDBSHaqIyyiujc9_9Cfj8EUqmwRI6CJj7PBrfxODIFEyM_SqgX4XvV0Ei9GIushrVO_5mvDchQISJ3ApCgFOxkpEyQs_m1zAFfVxFOtP0rfAcEGg2ZcXlNmRU-klT-M6DEVRzi4CTlkXG8gjxDbjNBl4CfPONq78OUuCUEeCQaYReTqA7b_qlP_ron6yfohvHbxfi6MPy4y66STxoYesmbA9tdevePEbX9FlXt-snw9T7BQQHMpU |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Genome+sequencing+of+the+extinct+Eurasian+wild+aurochs%2C+Bos+primigenius%2C+illuminates+the+phylogeography+and+evolution+of+cattle&rft.jtitle=Genome+Biology&rft.au=Park%2C+Stephen+D+E&rft.au=Magee%2C+David+A&rft.au=McGettigan%2C+Paul+A&rft.au=Teasdale%2C+Matthew+D&rft.date=2015-10-26&rft.pub=Springer+Nature+B.V&rft.issn=1474-7596&rft.eissn=1474-760X&rft.volume=16&rft_id=info:doi/10.1186%2Fs13059-015-0790-2 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1474-760X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1474-760X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1474-760X&client=summon |