Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer

Background 5-Fluorouracil (5-FU) has been commonly prescribed for patients with colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in CRC. Recently, microRNAs (miRNAs) have been established as a means of reversing the dilemma by regulating signaling pathways invol...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Journal of nanobiotechnology Ročník 18; číslo 1; s. 10 - 15
Hlavní autoři:	Liang, Gaofeng, Zhu, Yanliang, Ali, Doulathunnisa Jaffar, Tian, Tian, Xu, Huantian, Si, Ke, Sun, Bo, Chen, Baoan, Xiao, Zhongdang
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 09.01.2020 BioMed Central Ltd Springer Nature B.V BMC
Témata:	5-Fluorouracil 5-FU Anticancer properties Apoptosis Biological products Biotechnology Cancer cells Cancer patients Cancer therapies Care and treatment Cell cycle Chemistry Chemistry and Materials Science Chemotherapy Colon Colon cancer Colorectal cancer Colorectal carcinoma Cytotoxicity Delivery system Deoxyribonucleic acid Development and progression DNA DNA methylation Drug delivery systems Drug resistance Drug therapy Electroporation ErbB-2 protein Exosomes Fluorouracil Health aspects Inhibitors Membranes MicroRNA miR-21 inhibitor miRNA Molecular Medicine Nanotechnology Oligonucleotides Proteins PTEN protein Ribonucleic acid RNA Toxicity Tumors China Delivery system miR-21 inhibitor Exosomes Drug resistance 5-FU
ISSN:	1477-3155, 1477-3155
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!