Conserved phylogenetic distribution and limited antibiotic resistance of class 1 integrons revealed by assessing the bacterial genome and plasmid collection

Background Integrons, especially the class 1 integrons, are major contributors to the acquisition and dissemination of antibiotic resistance genes (ARGs). However, comprehensive knowledge of the types, content, and distribution of integrons in bacterial taxa is lacking to evaluate their contribution...

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Bibliographic Details
Published in:	Microbiome Vol. 6; no. 1; pp. 130 - 14
Main Authors:	Zhang, An Ni, Li, Li-Guan, Ma, Liping, Gillings, Michael R., Tiedje, James M., Zhang, Tong
Format:	Journal Article
Language:	English
Published:	London BioMed Central 21.07.2018 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Analysis Anopheles Antibiotic resistance Antibiotics Bacteria Bacterial genetics Bioinformatics Biomedical and Life Sciences Biomedicine Chromosomes Class 1 integrons Database construction Drug resistance Drug resistance in microorganisms Drug Resistance, Bacterial Evolution, Molecular Gammaproteobacteria - drug effects Gammaproteobacteria - genetics Gene transfer Gene Transfer, Horizontal Genes Genome, Bacterial Genomes Genomics Genotypes Identification Integrase Integrons Medical Microbiology Microbial Ecology Microbial Genetics and Genomics Microbiology Nonnative species Phylogenetics Phylogeny Plasmids Plasmids - genetics Sequence Analysis, DNA Software Spreading Studies Virology Whole genome analysis Database construction Class 1 integrons Bioinformatics Whole genome analysis Antibiotic resistance
ISSN:	2049-2618, 2049-2618
Online Access:	Get full text
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