The optimality of the standard genetic code assessed by an eight-objective evolutionary algorithm

Background The standard genetic code (SGC) is a unique set of rules which assign amino acids to codons. Similar amino acids tend to have similar codons indicating that the code evolved to minimize the costs of amino acid replacements in proteins, caused by mutations or translational errors. However,...

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Bibliographic Details
Published in:	BMC evolutionary biology Vol. 18; no. 1; pp. 192 - 18
Main Authors:	Wnętrzak, Małgorzata, Błażej, Paweł, Mackiewicz, Dorota, Mackiewicz, Paweł
Format:	Journal Article
Language:	English
Published:	London BioMed Central 13.12.2018 BioMed Central Ltd BMC
Subjects:	Algorithms Amino acids Amino Acids - genetics Animal Systematics/Taxonomy/Biogeography Biological research Biomedical and Life Sciences Codes Codon - genetics Codons Cost engineering Discriminant Analysis Entomology Evolution Evolution, Molecular Evolutionary algorithms Evolutionary Biology Genetic algorithm Genetic algorithms Genetic Code Genetics and Population Dynamics Genome evolution and evolutionary systems biology Genomes Hypotheses Life Sciences Models, Genetic Multiple objective analysis Mutation Operator Regions, Genetic - genetics Optimization Organisms Physicochemical properties Properties (attributes) Proteins Research Article Researchers Standard genetic code Transfer RNA Translation Evolution Standard genetic code Translation Mutation Genetic algorithm Optimization
ISSN:	1471-2148, 1471-2148
Online Access:	Get full text
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