Direct cell reprogramming for tissue engineering and regenerative medicine

Direct cell reprogramming, also called transdifferentiation, allows for the reprogramming of one somatic cell type directly into another, without the need to transition through an induced pluripotent state. Thus, it is an attractive approach to develop novel tissue engineering applications to treat...

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Bibliographic Details
Published in:	Journal of biological engineering Vol. 13; no. 1; pp. 14 - 15
Main Authors:	Grath, Alexander, Dai, Guohao
Format:	Journal Article
Language:	English
Published:	London BioMed Central 13.02.2019 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Animal models Apoptosis Applied Microbiology Biological Techniques Biomedical Engineering and Bioengineering Biotechnology Blood vessels Brain Brain injury Cartilage Cell division Cell reprogramming Clinical trials CRISPR Damage localization Disease DNA binding proteins Emerging leaders in biological engineering Endothelial cells Endothelium Engineering Environmental Engineering/Biotechnology Epigenetic inheritance Epigenetics Gene editing Genes Genetic engineering Grafts Heart attack Injuries Liver Liver diseases Medical research Medicine Methods Myocytes Nervous system diseases Neurodegenerative diseases Neurological diseases Neurons Nuclear reprogramming Nucleic Acid Chemistry Organ transplantation Phenotypes Physiological aspects Pluripotency Proteins Recovery of function Regeneration (physiology) Regenerative medicine Review Shortages Smooth muscle Somatic cells Stem cells Surgery Tissue engineering Transcription (Genetics) Transcription factors Transdifferentiation Vectors (Biology) United States Epigenetics Cell reprogramming Tissue engineering Transdifferentiation Gene editing Stem cells
ISSN:	1754-1611, 1754-1611
Online Access:	Get full text
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