Variability of risk factors and diabetes complications

Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when...

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Vydáno v:	Cardiovascular Diabetology Ročník 20; číslo 1; s. 101 - 11
Hlavní autoři:	Ceriello, Antonio, Prattichizzo, Francesco
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Springer Science and Business Media LLC 07.05.2021 BioMed Central Springer Nature B.V BMC
Témata:	Angiology Blood pressure Blood pressure variability Body weight Body weight variability Cardiology Cardiovascular disease Cholesterol Diabetes Diabetes Complications Diabetes mellitus Diseases of the circulatory (Cardiovascular) system Glucose variability Heart attacks Heart failure Heart rate Humans Hypertension Insulin Lipids Lipids variability Medicine Medicine & Public Health Mortality Oxidative stress Prognosis RC666-701 Review Risk Assessment Risk Factors Triglycerides Uric acid Uric acid variability Glucose variability Oxidative stress Diabetes mellitus Blood pressure variability Body weight variability Uric acid variability Microvascular complications Heart rate variability Lipids variability Cardiovascular complications
ISSN:	1475-2840, 1475-2840
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Abstract	Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability.
AbstractList	Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability. Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability.Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability. Abstract Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body weight, and serum uric acid, might play a role in the development of diabetes complications. Moreover, the variability of each risk factor, when contemporarily present, may have additive effects. However, the question is whether variability is causal or a marker. Evidence shows that the quality of care and the attainment of the target impact on the variability of all risk factors. On the other hand, for some of them causality may be considered. Although specific studies are still lacking, it should be useful checking the variability of a risk factor, together with its magnitude out of the normal range, in clinical practice. This can lead to an improvement of the quality of care, which, in turn, could further hesitate in an improvement of risk factors variability.
ArticleNumber	101
Author	Francesco Prattichizzo Antonio Ceriello
Author_xml	– sequence: 1 givenname: Antonio surname: Ceriello fullname: Ceriello, Antonio email: antonio.ceriello@hotmail.it organization: IRCCS MultiMedica – sequence: 2 givenname: Francesco orcidid: 0000-0002-2959-2658 surname: Prattichizzo fullname: Prattichizzo, Francesco email: francesco.prattichizzo@multimedica.it organization: IRCCS MultiMedica
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Keywords	Glucose variability Oxidative stress Diabetes mellitus Blood pressure variability Body weight variability Uric acid variability Microvascular complications Heart rate variability Lipids variability Cardiovascular complications
Language	English
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Snippet	Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate, body... Abstract Several studies suggest that, together with glucose variability, the variability of other risk factors, as blood pressure, plasma lipids, heart rate,...
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SubjectTerms	Angiology Blood pressure Blood pressure variability Body weight Body weight variability Cardiology Cardiovascular disease Cholesterol Diabetes Diabetes Complications Diabetes mellitus Diseases of the circulatory (Cardiovascular) system Glucose variability Heart attacks Heart failure Heart rate Humans Hypertension Insulin Lipids Lipids variability Medicine Medicine & Public Health Mortality Oxidative stress Prognosis RC666-701 Review Risk Assessment Risk Factors Triglycerides Uric acid Uric acid variability
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Title	Variability of risk factors and diabetes complications
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