The association between body mass index class and coronavirus disease 2019 outcomes

A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study's primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. Data on consecutive adult patients hospitalized with laboratory-confi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:International Journal of Obesity Ročník 45; číslo 3; s. 700 - 705
Hlavní autoři: Al-Salameh, Abdallah, Lanoix, Jean-Philippe, Bennis, Youssef, Andrejak, Claire, Brochot, Etienne, Deschasse, Guillaume, Dupont, Hervé, Goeb, Vincent, Jaureguy, Maité, Lion, Sylvie, Maizel, Julien, Moyet, Julien, Vaysse, Benoit, Desailloud, Rachel, Ganry, Olivier, Schmit, Jean-Luc, Lalau, Jean-Daniel
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Nature Publishing Group 01.03.2021
Témata:
Aged
Aged, 80 and over
Body Mass Index
Body size
Body weight
Categories
Confidence intervals
Coronaviridae
Coronaviruses
COVID-19
COVID-19 - complications
COVID-19 - epidemiology
COVID-19 - mortality
COVID-19 - therapy
Death
Female
France
Hospitalization - statistics & numerical data
Humans
Intensive Care Units
Male
Mortality
Obesity
Obesity - complications
Overweight
Overweight - complications
Regression analysis
Retrospective Studies
Statistical analysis
Underweight
Viral diseases
France
ISSN:0307-0565, 1476-5497, 1476-5497
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study's primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19. Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis. In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77-3.24] and 2.58 [1.28-5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29-8.06]) and obesity (3.05 [1.25-7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment. Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:0307-0565
1476-5497
1476-5497
DOI:10.1038/s41366-020-00721-1