Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples

Due to its cost effectiveness, next generation sequencing of pools of individuals (Pool‐Seq) is becoming a popular strategy for genome‐wide estimation of allele frequencies in population samples. As the allele frequency spectrum provides information about past episodes of selection, Pool‐seq is also...

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Bibliographic Details
Published in:	Molecular ecology resources Vol. 13; no. 2; pp. 337 - 340
Main Authors:	Boitard, Simon, Kofler, Robert, Françoise, Pierre, Robelin, David, Schlötterer, Christian, Futschik, Andreas
Format:	Journal Article
Language:	English
Published:	Oxford Blackwell Publishing Ltd 01.03.2013 Blackwell Wiley Subscription Services, Inc Wiley/Blackwell
Subjects:	allele frequency spectrum Amphibia. Reptilia Animal and plant ecology Animal, plant and microbial ecology Animals Biological and medical sciences Computer programs computer software cost effectiveness design detection estimation Fundamental and applied biological sciences. Psychology Gene Frequency General aspects Genetics Genetics of eukaryotes. Biological and molecular evolution genomics Genomics - instrumentation hidden Markov models High-Throughput Nucleotide Sequencing information Internet Life Sciences Models, Genetic next generation sequencing Polymorphism, Single Nucleotide pooled DNA population Population genetics Population genetics, reproduction patterns Quail - genetics Resource sampling selective sweeps Sequence Analysis, DNA - instrumentation Software Synecology Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution allele frequency spectrum Program next generation sequencing pooled DNA Markov model Ophidia Spectrum hidden Markov models Vertebrata Gene frequency DNA Reptilia selective sweeps Sequencing hidden markov model pooled dna selective sweep newt generation sequencing
ISSN:	1755-098X, 1755-0998, 1755-0998
Online Access:	Get full text
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