Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

Background Adapter trimming is a prerequisite step for analyzing next-generation sequencing (NGS) data when the reads are longer than the target DNA/RNA fragments. Although typically used in small RNA sequencing, adapter trimming is also used widely in other applications, such as genome DNA sequenci...

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Bibliographic Details
Published in:	BMC bioinformatics Vol. 15; no. 1; p. 182
Main Authors:	Jiang, Hongshan, Lei, Rong, Ding, Shou-Wei, Zhu, Shuifang
Format:	Journal Article
Language:	English
Published:	London BioMed Central 12.06.2014 BioMed Central Ltd Springer Nature B.V
Subjects:	Algorithms Analysis Animals Arabidopsis Bioinformatics Biomedical and Life Sciences Caenorhabditis elegans Computational Biology/Bioinformatics Computer Appl. in Life Sciences Deoxyribonucleic acid DNA Drosophila Dynamic programming Genetic testing Genomes High-Throughput Nucleotide Sequencing - methods Humans Life Sciences Methodology Methodology Article Methods Microarrays RNA sequencing Sequence analysis (methods) Sequence Analysis, RNA Software Time Factors Approximate string matching Next generation sequencing Adapter trimming Barcode demultiplexing Local sequence alignment
ISSN:	1471-2105, 1471-2105
Online Access:	Get full text
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