Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations

Temporal lobe epilepsy (TLE) is a prevalent neurological disorder resulting in disruptive seizures. In the case of drug resistant epilepsy resective surgery is often considered. This is a procedure hampered by unpredictable success rates, with many patients continuing to have seizures even after sur...

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Vydané v:	PLoS computational biology Ročník 11; číslo 12; s. e1004642
Hlavní autori:	Hutchings, Frances, Han, Cheol E., Keller, Simon S., Weber, Bernd, Taylor, Peter N., Kaiser, Marcus
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Public Library of Science 01.12.2015 Public Library of Science (PLoS)
Predmet:	Adult Aged Care and treatment Computer Simulation Connectome - methods Councils Diffusion Tensor Imaging - methods Epilepsy Epilepsy, Temporal Lobe - pathology Epilepsy, Temporal Lobe - surgery Excision (Surgery) Female Hippocampus - pathology Hippocampus - surgery Humans Male Methods Middle Aged Models, Anatomic Models, Neurological Monitoring, Intraoperative - methods Neurophysiological Monitoring - methods NMR Nuclear magnetic resonance Patient outcomes Patient-Specific Modeling Patients Preoperative Care - methods Public access Standard scores Success Surgery Surgery, Computer-Assisted - methods Temporal lobe epilepsy Treatment Outcome
ISSN:	1553-7358, 1553-734X, 1553-7358
On-line prístup:	Získať plný text
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