Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

Genome-wide association studies with metabolic traits (mGWAS) uncovered many genetic variants that influence human metabolism. These genetically influenced metabotypes (GIMs) contribute to our metabolic individuality, our capacity to respond to environmental challenges, and our susceptibility to spe...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	PLoS genetics Ročník 11; číslo 9; s. e1005487
Hlavní autoři:	Raffler, Johannes, Friedrich, Nele, Arnold, Matthias, Kacprowski, Tim, Rueedi, Rico, Altmaier, Elisabeth, Bergmann, Sven, Budde, Kathrin, Gieger, Christian, Homuth, Georg, Pietzner, Maik, Römisch-Margl, Werner, Strauch, Konstantin, Völzke, Henry, Waldenberger, Melanie, Wallaschofski, Henri, Nauck, Matthias, Völker, Uwe, Kastenmüller, Gabi, Suhre, Karsten
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 01.09.2015 Public Library of Science (PLoS)
Témata:	Biomedical research Chromosome Mapping Datasets Funding Gene expression Genetic aspects Genetic Predisposition to Disease Genome-wide association studies Genome-Wide Association Study Genomes Grants Homeostasis Humans Kidneys Medicine Metabolism Metabolites Metabolomics Methods Nuclear magnetic resonance spectroscopy Proton Magnetic Resonance Spectroscopy Quantitative Trait Loci Studies Urine
ISSN:	1553-7404, 1553-7390, 1553-7404
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!