Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

The dynamic changes of lymphocyte subsets and cytokines profiles of patients with novel coronavirus disease (COVID-19) and their correlation with the disease severity remain unclear. Peripheral blood samples were longitudinally collected from 40 confirmed COVID-19 patients and examined for lymphocyt...

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Bibliographic Details
Published in:	EBioMedicine Vol. 55; p. 102763
Main Authors:	Liu, Jing, Li, Sumeng, Liu, Jia, Liang, Boyun, Wang, Xiaobei, Wang, Hua, Li, Wei, Tong, Qiaoxia, Yi, Jianhua, Zhao, Lei, Xiong, Lijuan, Guo, Chunxia, Tian, Jin, Luo, Jinzhuo, Yao, Jinghong, Pang, Ran, Shen, Hui, Peng, Cheng, Liu, Ting, Zhang, Qian, Wu, Jun, Xu, Ling, Lu, Sihong, Wang, Baoju, Weng, Zhihong, Han, Chunrong, Zhu, Huabing, Zhou, Ruxia, Zhou, Helong, Chen, Xiliu, Ye, Pian, Zhu, Bin, Wang, Lu, Zhou, Wenqing, He, Shengsong, He, Yongwen, Jie, Shenghua, Wei, Ping, Zhang, Jianao, Lu, Yinping, Wang, Weixian, Zhang, Li, Li, Ling, Zhou, Fengqin, Wang, Jun, Dittmer, Ulf, Lu, Mengji, Hu, Yu, Yang, Dongliang, Zheng, Xin
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.05.2020 Elsevier
Subjects:	Adult Advanced Basic Science Aged Betacoronavirus - immunology CD8-Positive T-Lymphocytes - immunology China - epidemiology Comorbidity Coronavirus Coronavirus Infections - blood Coronavirus Infections - complications Coronavirus Infections - epidemiology Coronavirus Infections - immunology COVID-19 Cytokine Release Syndrome - etiology Cytokine Release Syndrome - immunology Cytokines - blood Female Flow Cytometry Humans Inflammatory cytokine Internal Medicine Leukocyte Count Lymphocyte Count Lymphocyte Subsets - immunology Lymphopenia Lymphopenia - etiology Male Middle Aged Neutrophils - immunology Pandemics Pneumonia, Viral - blood Pneumonia, Viral - complications Pneumonia, Viral - epidemiology Pneumonia, Viral - immunology Prognosis Research paper SARS-CoV-2 Time Factors China COVID-19 SARS-CoV-2 Coronavirus Lymphopenia Inflammatory cytokine
ISSN:	2352-3964, 2352-3964
Online Access:	Get full text
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