In vivo imaging of tau pathology using multi-parametric quantitative MRI

As the number of people diagnosed with Alzheimer's disease (AD) reaches epidemic proportions, there is an urgent need to develop effective treatment strategies to tackle the social and economic costs of this fatal condition. Dozens of candidate therapeutics are currently being tested in clinica...

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Vydáno v:	NeuroImage (Orlando, Fla.) Ročník 111; s. 369 - 378
Hlavní autoři:	Wells, J.A., O'Callaghan, J.M., Holmes, H.E., Powell, N.M., Johnson, R.A., Siow, B., Torrealdea, F., Ismail, O., Walker-Samuel, S., Golay, X., Rega, M., Richardson, S., Modat, M., Cardoso, M.J., Ourselin, S., Schwarz, A.J., Ahmed, Z., Murray, T.K., O'Neill, M.J., Collins, E.C., Colgan, N., Lythgoe, M.F.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.05.2015 Elsevier Limited Academic Press
Témata:	Alzheimer Disease - diagnosis Alzheimer's disease Animals Biocompatibility Biomarkers Brain Disease Models, Animal Female Imaging In vivo testing Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical research Medical services Mice Mice, Transgenic Neurodegeneration Pathology Proteins Rodents tau Proteins - metabolism Tauopathies - diagnosis
ISSN:	1053-8119, 1095-9572, 1095-9572
On-line přístup:	Získat plný text
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