A new test suggests hundreds of amino acid polymorphisms in humans are subject to balancing selection

The role that balancing selection plays in the maintenance of genetic diversity remains unresolved. Here, we introduce a new test, based on the McDonald–Kreitman test, in which the number of polymorphisms that are shared between populations is contrasted to those that are private at selected and neu...

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Veröffentlicht in:PLoS biology Jg. 20; H. 6; S. e3001645
Hauptverfasser: Soni, Vivak, Vos, Michiel, Eyre-Walker, Adam
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Public Library of Science 02.06.2022
Public Library of Science (PLoS)
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ISSN:1545-7885, 1544-9173, 1545-7885
Online-Zugang:Volltext
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