DNA repair of oxidative DNA damage in human carcinogenesis: Potential application for cancer risk assessment and prevention

Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosyla...

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Vydáno v:Cancer letters Ročník 266; číslo 1; s. 60 - 72
Hlavní autoři: Paz-Elizur, Tamar, Sevilya, Ziv, Leitner-Dagan, Yael, Elinger, Dalia, Roisman, Laila C., Livneh, Zvi
Médium: Journal Article
Jazyk:angličtina
Vydáno: Ireland Elsevier Ireland Ltd 18.07.2008
Elsevier Limited
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ISSN:0304-3835, 1872-7980
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Abstract Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
AbstractList Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Abstract Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1 , involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such as OGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in theMUTYHgene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary form of colorectal cancer. Extensive research efforts including biochemical, enzymological and genetic studies in model organisms established that the oxidative DNA lesion 8-oxoguanine is mutagenic, and that several DNA repair mechanisms operate to prevent its potentially mutagenic and carcinogenic outcome. Epidemiological studies on the association with sporadic cancers of single nucleotide polymorphisms in genes such asOGG1, involved in the repair of 8-oxoguanine yielded conflicting results, and suggest a minor effect at best. A new approach based on the functional analysis of DNA repair enzymatic activity showed that reduced activity of 8-oxoguanine DNA glycosylase (OGG) is a risk factor in lung and head and neck cancer. Moreover, the combination of smoking and low OGG activity was associated with a higher risk, suggesting a potential strategy for risk assessment and prevention of lung cancer, as well as other types of cancer.
Author Elinger, Dalia
Paz-Elizur, Tamar
Livneh, Zvi
Leitner-Dagan, Yael
Roisman, Laila C.
Sevilya, Ziv
Author_xml – sequence: 1
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  surname: Paz-Elizur
  fullname: Paz-Elizur, Tamar
– sequence: 2
  givenname: Ziv
  surname: Sevilya
  fullname: Sevilya, Ziv
– sequence: 3
  givenname: Yael
  surname: Leitner-Dagan
  fullname: Leitner-Dagan, Yael
– sequence: 4
  givenname: Dalia
  surname: Elinger
  fullname: Elinger, Dalia
– sequence: 5
  givenname: Laila C.
  surname: Roisman
  fullname: Roisman, Laila C.
– sequence: 6
  givenname: Zvi
  surname: Livneh
  fullname: Livneh, Zvi
  email: zvi.livneh@weizmann.ac.il
BackLink https://www.ncbi.nlm.nih.gov/pubmed/18374480$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1093/emboj/16.20.6314
10.1016/S0014-5793(00)01674-4
10.1021/bi00160a004
10.1182/blood-2005-10-4240
10.1093/nar/27.18.3638
10.1016/j.dnarep.2006.10.012
10.1515/BC.2002.098
10.1056/NEJMoa025283
10.1093/carcin/24.3.511
10.1158/0008-5472.CAN-06-4137
10.1074/jbc.M308658200
10.1158/0008-5472.CAN-06-4802
10.1385/1-59259-973-7:155
10.1089/omi.2006.10.499
10.1111/j.1349-7006.2007.00409.x
10.1080/00313020500169586
10.1038/355273a0
10.1016/S0921-8777(01)00096-9
10.1093/nar/29.2.449
10.1006/bbrc.1999.0649
10.1093/nar/29.2.430
10.1056/NEJMsa053935
10.1016/j.dnarep.2005.06.017
10.1038/35077232
10.1038/sj.onc.1206027
10.1073/pnas.050404497
10.1016/j.dnarep.2006.11.001
10.1042/bj3250001
10.1002/path.1958
10.1038/ng828
10.1086/500848
10.1006/abbi.2000.1773
10.3233/CBM-2007-3303
10.1002/1097-0215(20001101)88:3<325::AID-IJC1>3.0.CO;2-K
10.1158/0008-5472.CAN-06-2294
10.1126/science.7801122
10.1093/nar/28.6.1355
10.2144/05384SU04
10.1016/j.copbio.2006.06.013
10.1016/j.mrfmmm.2004.02.018
10.1016/S0960-9822(02)00863-1
10.1093/nar/gkl060
10.1023/B:BIGI.0000043957.03420.7e
10.1093/jnci/djg033
10.1038/21447
10.1158/1055-9965.EPI-14-7-ED
10.1158/0008-5472.CAN-03-3834
10.1097/01.cej.0000215612.98132.18
10.1093/nar/gki813
10.1093/carcin/21.3.361
10.1073/pnas.94.17.9463
10.1016/j.molcel.2004.06.003
10.3233/CBM-2005-12-308
10.1073/pnas.062053799
10.1016/j.mam.2007.05.005
10.1079/BJN20031001
10.1016/S0027-5107(02)00254-3
10.1016/j.dnarep.2006.08.003
10.1038/35002510
10.1016/S1097-2765(00)80346-9
10.1016/0168-9525(93)90089-Z
10.1038/349431a0
10.1016/S0065-230X(06)96003-5
10.1093/nar/gki325
10.1038/sj.emboj.7601277
10.1074/jbc.274.26.18201
10.1093/mutage/gem008
10.1073/pnas.90.3.1122
10.1093/nar/27.20.4001
10.1093/carcin/7.11.1849
10.1073/pnas.191086798
10.1007/s00018-003-3053-4
10.1073/pnas.96.23.13300
10.1016/j.dnarep.2006.10.022
10.1038/nm1087
10.1038/327077a0
10.1016/j.dnarep.2006.10.011
10.1038/35094000
10.1126/science.285.5425.263
10.1038/35077256
10.1093/jnci/92.21.1764
10.1006/geno.1994.1657
10.1080/10715769800300591
10.1002/ijc.20790
10.1021/bi00181a029
10.1016/0921-8777(91)90035-N
10.1038/sj.embor.embor838
10.1128/JB.181.19.6210-6213.1999
10.1093/aje/kwi318
10.1158/1055-9965.EPI-06-0712
10.1093/nar/27.5.1365
10.1016/j.dnarep.2006.10.008
10.1016/S0968-0004(00)89086-6
10.1016/S0960-9822(02)00686-3
10.1016/j.mrrev.2003.06.010
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Issue 1
Keywords DNA repair enzymatic activity
Oxidative stress
NSCLC
OGG1
PBMC
BER
Early detection
SNP
Functional DNA repair assay
HCR
ROS
8-Oxoguanine
NER
95% CI
non-small cell lung cancer
peripheral blood mononuclear cells
single nucleotide polymorphism
base excision repair
host-cell reactivation
95% confidence interval
reactive oxygen species
nucleotide excision repair
Language English
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Incumbent of The Maxwell Ellis Professorial Chair in Biomedical Research. To whom all correspondence should be addressed: Dr. Zvi Livneh, Dept. of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel. Tel: 972-8-934-3203; Fax: 972-8-934-4169; Email: zvi.livneh@weizmann.ac.il
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PublicationTitle Cancer letters
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References Klungland, Rosewell, Hollenbach, Larsen, Daly, Epe, Seeberg, Lindahl, Barnes (bib48) 1999; 96
Fujikawa, Kamiya, Yakushiji, Fujii, Nakabeppu, Kasai (bib16) 1999; 274
Shibutani, Takeshita, Grollman (bib13) 1991; 349
Dizdaroglu (bib85) 1998; 29
Avkin, Livneh (bib37) 2002; 510
Astley, Elliott, Archer, Southon (bib101) 2004; 91
Collins, Gaivao (bib93) 2007; 28
Luna, Rolseth, Hilrestrand, Otterlei, Dantzer, Bjoras, Seeberg (bib62) 2005; 33
Gulmann, Sheehan, Kay, Liotta, Petricoin (bib88) 2006; 208
Boiteux, Radicella (bib22) 2000; 377
Bartsch, Nair, Owen (bib81) 2002; 383
Kasai, Crain, Kuchino, Nishimura, Ootsuyama, Tanooka (bib10) 1986; 7
Cheadle, Sampson (bib56) 2007; 6
Gackowski, Speina, Zielinska, Kowalewski, Rozalski, Siomek, Paciorek, Tudek, Olinski (bib70) 2003; 63
Sakiyama, Kohno, Mimaki, Ohta, Yanagitani, Sobue, Kunitoh, Saito, Shimizu, Hirama, Kimura, Maeno, Hirose, Eguchi, Saito, Ohki, Yokota (bib65) 2005; 114
Paz-Elizur, Krupsky, Elinger, Schechtman, Livneh (bib77) 2005; 1
Paz-Elizur, Ben-Yosef, Elinger, Vexler, Krupsky, Berrebi, Shani, Schechtman, Freedman, Livneh (bib72) 2006; 66
Wiederhold, Leppard, Kedar, Karimi-Busheri, Rasouli-Nia, Weinfeld, Tomkinson, Izumi, Prasad, Wilson, Mitra, Hazra (bib30) 2004; 15
MacPherson, Barone, Maga, Mazzei, Karran, Bignami (bib44) 2005; 33
D’Errico, Parlanti, Teson, de Jesus, Degan, Calcagnile, Jaruga, Bjoras, Crescenzi, Pedrini, Egly, Zambruno, Stefanini, Dizdaroglu, Dogliotti (bib78) 2006; 25
Maruvada, Wang, Wagner, Srivastava (bib87) 2005
Xie, Yang, Cunanan, Okamoto, Shibata, Pan, Barnes, Lindahl, McIlhatton, Fishel, Miller (bib50) 2004; 64
Colussi, Parlanti, Degan, Aquilina, Barnes, MacPherson, Karran, Crescenzi, Dogliotti, Bignami (bib43) 2002; 12
Krokan, Nilsen, Skorpen, Otterlei, Slupphaug (bib20) 2000; 476
Dianov, Bischoff, Sunesen, Bohr (bib53) 1999; 27
Paz-Elizur, Elinger, Leitner-Dagan, Blumenstein, Krupsky, Berrebi, Schechtman, Livneh (bib73) 2007; 6
Klungland, Bjelland (bib45) 2007; 6
Ohtsubo, Nishioka, Imaiso, Iwai, Shimokawa, Oda, Fujiwara, Nakabeppu (bib39) 2000; 28
Spivak, Hanawalt (bib96) 2006; 5
Ishibashi, Hayakawa, Sekiguchi (bib18) 2003; 4
Tsuzuki, Egashira, Igarashi, Iwakuma, Nakatsuru, Tominaga, Kawate, Nakao, Nakamura, Ide, Kura, Nakabeppu, Katsuki, Ishikawa, Sekiguchi (bib52) 2001; 98
Janssen, Schlink, Gotte, Hippler, Kaina, Oesch (bib61) 2001; 486
Paz-Elizur, Elinger, Blumenstein, Krupsky, Schechtman, Livneh (bib76) 2007; 3
Bruner, Norman, Verdine (bib23) 2000; 403
Murphy, Millar, Lee (bib91) 2005; 37
Modrich (bib4) 1994; 266
Sakumi, Tominaga, Furuichi, Xu, Tsuzuki, Sekiguchi, Nakabeppu (bib49) 2003; 63
Peto (bib58) 2001; 411
Krokan, Standal, Slupphaug (bib24) 1997; 325
Furuichi, Yoshida, Oda, Tajiri, Nakabeppu, Tsuzuki, Sekiguchi (bib15) 1994; 24
Haab (bib86) 2006; 17
Pavlov, Minnick, Izuta, Kunkel (bib14) 1994; 33
Monden, Arai, Asano, Ohtsuka, Aburatani, Nishimura (bib75) 1999; 258
Chatterjee, Ionan, Draghici, Tainsky (bib90) 2006; 10
Parker, Eshleman (bib40) 2003; 60
Chung, Kasai, Jones, Inoue, Ishikawa, Ohtsuka, Nishimura (bib74) 1991; 254
Maki, Sekiguchi (bib11) 1992; 355
Vineis, Perera (bib82) 2001; 88
Collins (bib92) 2002; 203
Bjoras, Luna, Johnsen, Hoff, Haug, Rognes, Seeberg (bib32) 1997; 16
Wu, Gu, Grossman, Amos, Etzel, Huang, Zhang, Millikan, Lerner, Dinney, Spitz (bib66) 2006; 78
Dherin, Radicella, Dizdaroglu, Boiteux (bib59) 1999; 27
Farmer (bib79) 2004; 157
Hill, Hazra, Izumi, Mitra (bib25) 2001; 29
Ni, Marsischky, Kolodner (bib42) 1999; 4
Sidoremko, Nevinsky, Zharkov (bib26) 2007; 6
Wei, Cheng, Amos, Wang, Guo, Hong, Spitz (bib95) 2000; 92
Sears, Armstrong (bib89) 2007; 96
Paz-Elizur, Krupsky, Blumenstein, Elinger, Schechtman, Livneh (bib69) 2003; 95
Collins, Harrington, Drew, Melvin (bib100) 2003; 24
Fortini, Dogliotti (bib21) 2007; 6
Sieber, Lipton, Crabtree, Heinimann, Fidalgo, Phillips, Bisgaard, Orntoft, Aaltonen, Hodgson, Thomas, Tomlinson (bib57) 2003; 348
Friedberg, Walker, Siede, Wood, Schultz, Ellenberger (bib1) 2006
Ford, Ajani, Croft, Crichley, Labarthe, Kottke, Giles, Capewell (bib99) 2007; 356
Speina, Zielinska, Barbin, Gackowski, Kowalewski, Graziewicz, Siedlecki, Olinski, Tudek (bib71) 2003; 63
Minowa, Arai, Hirano, Monden, Nakai, Fukuda, Itoh, Takano, Hippou, Aburatani, Masumura, Nohmi, Nishimura, Noda (bib47) 2000; 97
Friedberg (bib7) 2001; 1
Seeberg, Eide, Bjoras (bib19) 1995; 20
Hoeijmakers (bib2) 2001; 411
Omenn (bib103) 2007; 16
Athas, Hedayati, Matanoski, Farmer, Grossman (bib94) 1991; 51
Osterod, Larsen, Le Page, Hengstler, van der Horst, Boiteux, Klungland, Epe (bib54) 2002; 21
Reardon, Bessho, Kung, Bolton, Sancar (bib31) 1997; 94
Sakamoto, Tominaga, Yamauchi, Nakatsu, Sakumi, Yoshiyama, Egashira, Kura, Yao, Tsuneyoshi, Maki, Nakabeppu, Tsuzuki (bib51) 2007; 67
Wu, Gu, Spitz (bib98) 2007; 67
Pitsikas, Lee, Rainbow (bib97) 2007; 22
Vogel, Nexo, Wallin, Overvad, Tjonneland, Raaschou-Nielsen (bib64) 2004; 42
Anson, Mason, Bohr (bib84) 2006; 314
Moller, Loft (bib102) 2004; 551
Moriya (bib36) 1993; 90
Tsuzuki, Nakatsu, Nakabeppu (bib46) 2007; 98
Sorensen, Autrup, Moller, Hertel, Jensen, Vinzents, Knudsen, Loft (bib80) 2003; 544
Kuchino, Mori, Kasai, Inoue, Iwai, Miura, Ohtsuka, Nishimura (bib12) 1987; 327
Takao, Zhang, Yonei, Yasui (bib35) 1999; 27
Hayashi, Tominaga, Hirano, McKenna, Nakabeppu, Matsumoto (bib41) 2002; 12
Huang, Dinney, Lin, Lin, Grossman, Wu (bib67) 2007; 16
Dou, Mitra, Hazra (bib29) 2003; 278
Hung, Hall, Brennan, Boffetta (bib63) 2005; 162
Hill, Evans (bib60) 2006; 34
Taniguchi, D’Andrea (bib6) 2006; 107
Marnett (bib83) 2000; 21
Slupska, Luther, Chiang, Yang, Miller (bib34) 1999; 181
Michaels, Tchou, Grollman, Miller (bib33) 1992; 31
Hazra, Izumi, Boldogh, Imhoff, Kow, Jaruga, Dizdaroglu, Mitra (bib27) 2002; 99
Grollman, Moriya (bib38) 1993; 9
Fujikawa, Kamiya, Yakushiji, Nakabeppu, Kasai (bib17) 2001; 29
Masutani, Kusumoto, Yamada, Dohmae, Yokoi, Yuasa, Araki, Iwai, Takio, Hanaoka (bib8) 1999; 399
Vogelstein, Kinzler (bib55) 1998
Hazra, Das, Das, Choudhury, Kow, Roy (bib28) 2007; 6
Paz-Elizur, Brenner, Livneh (bib68) 2005; 14
Al-Tassan, Chmiel, Maynard, Fleming, Livingston, Williams, Hodges, Davis, David, Sampson, Cheadle (bib5) 2002; 30
Johnson, Kondratick, Prakash, Prakash (bib9) 1999; 285
Vogelstein, Kinzler (bib3) 2004; 10
Reardon (10.1016/j.canlet.2008.02.032_bib31) 1997; 94
Maki (10.1016/j.canlet.2008.02.032_bib11) 1992; 355
Colussi (10.1016/j.canlet.2008.02.032_bib43) 2002; 12
Hayashi (10.1016/j.canlet.2008.02.032_bib41) 2002; 12
Krokan (10.1016/j.canlet.2008.02.032_bib20) 2000; 476
Dherin (10.1016/j.canlet.2008.02.032_bib59) 1999; 27
Wei (10.1016/j.canlet.2008.02.032_bib95) 2000; 92
Klungland (10.1016/j.canlet.2008.02.032_bib48) 1999; 96
Vogel (10.1016/j.canlet.2008.02.032_bib64) 2004; 42
Slupska (10.1016/j.canlet.2008.02.032_bib34) 1999; 181
Shibutani (10.1016/j.canlet.2008.02.032_bib13) 1991; 349
Sorensen (10.1016/j.canlet.2008.02.032_bib80) 2003; 544
Tsuzuki (10.1016/j.canlet.2008.02.032_bib46) 2007; 98
Xie (10.1016/j.canlet.2008.02.032_bib50) 2004; 64
Maruvada (10.1016/j.canlet.2008.02.032_bib87) 2005
Janssen (10.1016/j.canlet.2008.02.032_bib61) 2001; 486
D’Errico (10.1016/j.canlet.2008.02.032_bib78) 2006; 25
Wu (10.1016/j.canlet.2008.02.032_bib98) 2007; 67
Boiteux (10.1016/j.canlet.2008.02.032_bib22) 2000; 377
Sears (10.1016/j.canlet.2008.02.032_bib89) 2007; 96
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib76) 2007; 3
Wu (10.1016/j.canlet.2008.02.032_bib66) 2006; 78
Sieber (10.1016/j.canlet.2008.02.032_bib57) 2003; 348
Ishibashi (10.1016/j.canlet.2008.02.032_bib18) 2003; 4
Collins (10.1016/j.canlet.2008.02.032_bib100) 2003; 24
Haab (10.1016/j.canlet.2008.02.032_bib86) 2006; 17
Krokan (10.1016/j.canlet.2008.02.032_bib24) 1997; 325
Vogelstein (10.1016/j.canlet.2008.02.032_bib55) 1998
Wiederhold (10.1016/j.canlet.2008.02.032_bib30) 2004; 15
Osterod (10.1016/j.canlet.2008.02.032_bib54) 2002; 21
Vogelstein (10.1016/j.canlet.2008.02.032_bib3) 2004; 10
Athas (10.1016/j.canlet.2008.02.032_bib94) 1991; 51
Al-Tassan (10.1016/j.canlet.2008.02.032_bib5) 2002; 30
Dou (10.1016/j.canlet.2008.02.032_bib29) 2003; 278
Sakiyama (10.1016/j.canlet.2008.02.032_bib65) 2005; 114
Omenn (10.1016/j.canlet.2008.02.032_bib103) 2007; 16
Monden (10.1016/j.canlet.2008.02.032_bib75) 1999; 258
Ohtsubo (10.1016/j.canlet.2008.02.032_bib39) 2000; 28
Hoeijmakers (10.1016/j.canlet.2008.02.032_bib2) 2001; 411
Dizdaroglu (10.1016/j.canlet.2008.02.032_bib85) 1998; 29
Klungland (10.1016/j.canlet.2008.02.032_bib45) 2007; 6
Michaels (10.1016/j.canlet.2008.02.032_bib33) 1992; 31
Johnson (10.1016/j.canlet.2008.02.032_bib9) 1999; 285
Grollman (10.1016/j.canlet.2008.02.032_bib38) 1993; 9
Moller (10.1016/j.canlet.2008.02.032_bib102) 2004; 551
Hill (10.1016/j.canlet.2008.02.032_bib60) 2006; 34
Fortini (10.1016/j.canlet.2008.02.032_bib21) 2007; 6
Sidoremko (10.1016/j.canlet.2008.02.032_bib26) 2007; 6
Minowa (10.1016/j.canlet.2008.02.032_bib47) 2000; 97
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib68) 2005; 14
Bjoras (10.1016/j.canlet.2008.02.032_bib32) 1997; 16
Chung (10.1016/j.canlet.2008.02.032_bib74) 1991; 254
Gackowski (10.1016/j.canlet.2008.02.032_bib70) 2003; 63
Kasai (10.1016/j.canlet.2008.02.032_bib10) 1986; 7
Fujikawa (10.1016/j.canlet.2008.02.032_bib16) 1999; 274
Hazra (10.1016/j.canlet.2008.02.032_bib28) 2007; 6
Anson (10.1016/j.canlet.2008.02.032_bib84) 2006; 314
Hill (10.1016/j.canlet.2008.02.032_bib25) 2001; 29
MacPherson (10.1016/j.canlet.2008.02.032_bib44) 2005; 33
Ford (10.1016/j.canlet.2008.02.032_bib99) 2007; 356
Ni (10.1016/j.canlet.2008.02.032_bib42) 1999; 4
Speina (10.1016/j.canlet.2008.02.032_bib71) 2003; 63
Sakamoto (10.1016/j.canlet.2008.02.032_bib51) 2007; 67
Friedberg (10.1016/j.canlet.2008.02.032_bib1) 2006
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib72) 2006; 66
Marnett (10.1016/j.canlet.2008.02.032_bib83) 2000; 21
Huang (10.1016/j.canlet.2008.02.032_bib67) 2007; 16
Taniguchi (10.1016/j.canlet.2008.02.032_bib6) 2006; 107
Modrich (10.1016/j.canlet.2008.02.032_bib4) 1994; 266
Bruner (10.1016/j.canlet.2008.02.032_bib23) 2000; 403
Avkin (10.1016/j.canlet.2008.02.032_bib37) 2002; 510
Masutani (10.1016/j.canlet.2008.02.032_bib8) 1999; 399
Takao (10.1016/j.canlet.2008.02.032_bib35) 1999; 27
Tsuzuki (10.1016/j.canlet.2008.02.032_bib52) 2001; 98
Pavlov (10.1016/j.canlet.2008.02.032_bib14) 1994; 33
Cheadle (10.1016/j.canlet.2008.02.032_bib56) 2007; 6
Hazra (10.1016/j.canlet.2008.02.032_bib27) 2002; 99
Vineis (10.1016/j.canlet.2008.02.032_bib82) 2001; 88
Kuchino (10.1016/j.canlet.2008.02.032_bib12) 1987; 327
Friedberg (10.1016/j.canlet.2008.02.032_bib7) 2001; 1
Murphy (10.1016/j.canlet.2008.02.032_bib91) 2005; 37
Gulmann (10.1016/j.canlet.2008.02.032_bib88) 2006; 208
Furuichi (10.1016/j.canlet.2008.02.032_bib15) 1994; 24
Chatterjee (10.1016/j.canlet.2008.02.032_bib90) 2006; 10
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib77) 2005; 1
Luna (10.1016/j.canlet.2008.02.032_bib62) 2005; 33
Parker (10.1016/j.canlet.2008.02.032_bib40) 2003; 60
Fujikawa (10.1016/j.canlet.2008.02.032_bib17) 2001; 29
Seeberg (10.1016/j.canlet.2008.02.032_bib19) 1995; 20
Peto (10.1016/j.canlet.2008.02.032_bib58) 2001; 411
Farmer (10.1016/j.canlet.2008.02.032_bib79) 2004; 157
Hung (10.1016/j.canlet.2008.02.032_bib63) 2005; 162
Astley (10.1016/j.canlet.2008.02.032_bib101) 2004; 91
Moriya (10.1016/j.canlet.2008.02.032_bib36) 1993; 90
Collins (10.1016/j.canlet.2008.02.032_bib92) 2002; 203
Sakumi (10.1016/j.canlet.2008.02.032_bib49) 2003; 63
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib69) 2003; 95
Dianov (10.1016/j.canlet.2008.02.032_bib53) 1999; 27
Bartsch (10.1016/j.canlet.2008.02.032_bib81) 2002; 383
Collins (10.1016/j.canlet.2008.02.032_bib93) 2007; 28
Spivak (10.1016/j.canlet.2008.02.032_bib96) 2006; 5
Pitsikas (10.1016/j.canlet.2008.02.032_bib97) 2007; 22
Paz-Elizur (10.1016/j.canlet.2008.02.032_bib73) 2007; 6
References_xml – volume: 411
  start-page: 390
  year: 2001
  end-page: 395
  ident: bib58
  article-title: Cancer epidemiology in the last century and the next decade
  publication-title: Nature
– volume: 383
  start-page: 915
  year: 2002
  end-page: 921
  ident: bib81
  article-title: Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: potential role of lipid peroxidation, dietary fat and antioxidants
  publication-title: Biol. Chem.
– volume: 25
  start-page: 4305
  year: 2006
  end-page: 4315
  ident: bib78
  article-title: New functions of XPC in the protection of human skin cells from oxidative damage
  publication-title: EMBO J.
– volume: 17
  start-page: 415
  year: 2006
  end-page: 421
  ident: bib86
  article-title: Applications of antibody array platforms
  publication-title: Curr. Opin. Biotechnol.
– volume: 15
  start-page: 209
  year: 2004
  end-page: 220
  ident: bib30
  article-title: AP endonuclease-independent DNA base excision repair in human cells
  publication-title: Mol. Cell
– year: 2006
  ident: bib1
  article-title: DNA Repair and Mutagenesis
– volume: 29
  start-page: 551
  year: 1998
  end-page: 563
  ident: bib85
  article-title: Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry
  publication-title: Free Radic. Res.
– volume: 486
  start-page: 207
  year: 2001
  end-page: 216
  ident: bib61
  article-title: DNA repair activity of 8-oxoguanine DNA glycosylase I (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326
  publication-title: Mutat. Res.
– volume: 314
  start-page: 155
  year: 2006
  end-page: 181
  ident: bib84
  article-title: Gene-specific and mitochondrial repair of oxidative DNA damage
  publication-title: Methods Mol. Biol.
– volume: 551
  start-page: 79
  year: 2004
  end-page: 89
  ident: bib102
  article-title: Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair
  publication-title: Mutat. Res.
– volume: 20
  start-page: 391
  year: 1995
  end-page: 397
  ident: bib19
  article-title: The base excision repair pathway
  publication-title: Trends Biochem. Sci.
– volume: 34
  start-page: 1620
  year: 2006
  end-page: 1632
  ident: bib60
  article-title: Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase
  publication-title: Nucl. Acids Res.
– volume: 356
  start-page: 2388
  year: 2007
  end-page: 2398
  ident: bib99
  article-title: Explaining the decrease in US deaths from coronary disease, 1980–2000
  publication-title: N. Engl. J. Med.
– volume: 411
  start-page: 366
  year: 2001
  end-page: 374
  ident: bib2
  article-title: Genome maintenance mechanisms for preventing cancer
  publication-title: Nature
– volume: 285
  start-page: 263
  year: 1999
  end-page: 265
  ident: bib9
  article-title: hRAD30 mutations in the variant form of xeroderma pigmentosum
  publication-title: Science
– volume: 28
  start-page: 1355
  year: 2000
  end-page: 1364
  ident: bib39
  article-title: Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria
  publication-title: Nucl. Acids Res.
– volume: 88
  start-page: 325
  year: 2001
  end-page: 328
  ident: bib82
  article-title: DNA adducts as markers of exposure to carcinogens and risk of cancer
  publication-title: Int. J. Cancer
– volume: 33
  start-page: 1813
  year: 2005
  end-page: 1824
  ident: bib62
  article-title: Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harboring the hOGG1-Cys326 polymorphic variant
  publication-title: Nucl. Acids Res.
– volume: 7
  start-page: 1849
  year: 1986
  end-page: 1851
  ident: bib10
  article-title: Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
  publication-title: Carcinogenesis
– volume: 94
  start-page: 9463
  year: 1997
  end-page: 9468
  ident: bib31
  article-title: In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 4
  start-page: 439
  year: 1999
  end-page: 444
  ident: bib42
  article-title: MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in
  publication-title: Mol. Cell
– volume: 274
  start-page: 18201
  year: 1999
  end-page: 18205
  ident: bib16
  article-title: The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
  publication-title: J. Biol. Chem.
– volume: 91
  start-page: 63
  year: 2004
  end-page: 72
  ident: bib101
  article-title: Evidence that dietary supplementation with carotenoids and carotenoid-rich foods modulates the DNA damage:repair balance in human lymphocytes
  publication-title: Br. J. Nutr.
– volume: 10
  start-page: 789
  year: 2004
  end-page: 799
  ident: bib3
  article-title: Cancer genes and the pathways they control
  publication-title: Nat. Med.
– volume: 6
  start-page: 317
  year: 2007
  end-page: 328
  ident: bib26
  article-title: Mechanism of interaction between human 8-oxoguanine-DNA glycosylase and AP endonuclease
  publication-title: DNA Repair
– volume: 27
  start-page: 3638
  year: 1999
  end-page: 3644
  ident: bib35
  article-title: Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase
  publication-title: Nucl. Acids Res.
– volume: 98
  start-page: 11456
  year: 2001
  end-page: 11461
  ident: bib52
  article-title: Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 349
  start-page: 431
  year: 1991
  end-page: 434
  ident: bib13
  article-title: Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
  publication-title: Nature
– volume: 27
  start-page: 4001
  year: 1999
  end-page: 40007
  ident: bib59
  article-title: Excision of oxidatively damaged DNA bases by the human alpha-hOGG1 protein and the polymorphic alpha-hOGG1-(Ser326/Cys326) protein which is frequently found in human populations
  publication-title: Nucl. Acids Res.
– volume: 24
  start-page: 485
  year: 1994
  end-page: 490
  ident: bib15
  article-title: Genomic structure and chromosome location of the human MutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to G:C transversion
  publication-title: Genomics
– volume: 348
  start-page: 791
  year: 2003
  end-page: 799
  ident: bib57
  article-title: Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
  publication-title: N. Engl. J. Med.
– volume: 9
  start-page: 246
  year: 1993
  end-page: 249
  ident: bib38
  article-title: Mutagenesis by 8-oxoguanine: an enemy within
  publication-title: Trends Genet.
– volume: 78
  start-page: 464
  year: 2006
  end-page: 479
  ident: bib66
  article-title: Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes
  publication-title: Am. J. Hum. Genet.
– volume: 377
  start-page: 1
  year: 2000
  end-page: 8
  ident: bib22
  article-title: The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis
  publication-title: Arch. Biochem. Biophys.
– volume: 96
  start-page: 13,300
  year: 1999
  end-page: 13,305
  ident: bib48
  article-title: Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 64
  start-page: 3096
  year: 2004
  end-page: 3102
  ident: bib50
  article-title: Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of K-Ras oncogene in lung tumors
  publication-title: Cancer Res.
– volume: 510
  start-page: 81
  year: 2002
  end-page: 90
  ident: bib37
  article-title: Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative lesion 8-oxoguanine in human cells
  publication-title: Mutat. Res.
– volume: 6
  start-page: 398
  year: 2007
  end-page: 409
  ident: bib21
  article-title: Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways
  publication-title: DNA Repair
– volume: 327
  start-page: 77
  year: 1987
  end-page: 79
  ident: bib12
  article-title: Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
  publication-title: Nature
– volume: 98
  start-page: 465
  year: 2007
  end-page: 470
  ident: bib46
  article-title: Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis
  publication-title: Cancer Sci.
– volume: 37
  start-page: 271
  year: 2005
  end-page: 277
  ident: bib91
  article-title: Gene expression profiling in breast cancer: towards individualising patient management
  publication-title: Pathology
– volume: 67
  start-page: 3493
  year: 2007
  end-page: 3495
  ident: bib98
  article-title: Mutagen sensitivity: a genetic predisposition factor for cancer
  publication-title: Cancer Res.
– volume: 1
  start-page: 22
  year: 2001
  end-page: 33
  ident: bib7
  article-title: How nucleotide excision repair protects against cancer
  publication-title: Nat. Rev. Cancer
– volume: 21
  start-page: 361
  year: 2000
  end-page: 370
  ident: bib83
  article-title: Oxyradicals and DNA damage
  publication-title: Carcinogenesis
– volume: 5
  start-page: 13
  year: 2006
  end-page: 22
  ident: bib96
  article-title: Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts
  publication-title: DNA Repair
– volume: 325
  start-page: 1
  year: 1997
  end-page: 16
  ident: bib24
  article-title: DNA glycosylases in the base excision repair of DNA
  publication-title: Biochem. J.
– volume: 28
  start-page: 307
  year: 2007
  end-page: 322
  ident: bib93
  article-title: DNA base excision repair as a biomarker in molecular epidemiology studies
  publication-title: Mol. Aspects Med.
– volume: 60
  start-page: 2064
  year: 2003
  end-page: 2083
  ident: bib40
  article-title: Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis
  publication-title: Cell. Mol. Life Sci.
– volume: 29
  start-page: 449
  year: 2001
  end-page: 454
  ident: bib17
  article-title: Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP
  publication-title: Nucl. Acids Res.
– volume: 403
  year: 2000
  ident: bib23
  article-title: Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
  publication-title: Nature
– volume: 90
  start-page: 1122
  year: 1993
  end-page: 1126
  ident: bib36
  article-title: Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted GC to TA transversions in simian kidney cells
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 157
  start-page: 71
  year: 2004
  end-page: 90
  ident: bib79
  article-title: Exposure biomarkers for the study of toxicological impact on carcinogenic processes
  publication-title: IARC Sci. Publ.
– volume: 63
  start-page: 4899
  year: 2003
  end-page: 4902
  ident: bib70
  article-title: Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer
  publication-title: Cancer Res.
– volume: 3
  start-page: 129
  year: 2007
  end-page: 133
  ident: bib76
  article-title: Novel molecular targets for risk identification: DNA repair enzyme activities
  publication-title: Cancer Biomarkers
– volume: 24
  start-page: 511
  year: 2003
  end-page: 515
  ident: bib100
  article-title: Nutritional modulation of DNA repair in human intervention study
  publication-title: Carcinogenesis
– volume: 42
  start-page: 453
  year: 2004
  end-page: 460
  ident: bib64
  article-title: No association between base excision repair gene polymorphism and risk of lung cancer
  publication-title: Biochem. Genet.
– volume: 12
  start-page: 3350339
  year: 2002
  ident: bib41
  article-title: Replication-associated repair of adenine:8-oxoguanine mispairs by MYH
  publication-title: Curr. Biol.
– volume: 27
  start-page: 1365
  year: 1999
  end-page: 1368
  ident: bib53
  article-title: Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells
  publication-title: Nucl. Acids. Res.
– volume: 10
  start-page: 499
  year: 2006
  end-page: 506
  ident: bib90
  article-title: Epitomics: global profiling of immune response to disease using protein microarrays
  publication-title: OMICS
– volume: 63
  start-page: 902
  year: 2003
  end-page: 905
  ident: bib49
  article-title: Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption
  publication-title: Cancer Res.
– volume: 33
  start-page: 4695
  year: 1994
  end-page: 4701
  ident: bib14
  article-title: DNA replication fidelity with 8-oxodeoxyguanosine triphosphate
  publication-title: Biochemistry
– volume: 254
  start-page: 1
  year: 1991
  end-page: 12
  ident: bib74
  article-title: An endonuclease activity of
  publication-title: Mutat. Res.
– volume: 16
  start-page: 6314
  year: 1997
  end-page: 6322
  ident: bib32
  article-title: Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
  publication-title: EMBO J.
– volume: 114
  start-page: 730
  year: 2005
  end-page: 737
  ident: bib65
  article-title: Association of amino acid substitution polymorphism in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk
  publication-title: Int. J. Cancer
– volume: 33
  start-page: 5094
  year: 2005
  end-page: 5105
  ident: bib44
  article-title: 8-Oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha
  publication-title: Nucl. Acids Res.
– volume: 14
  start-page: 1585
  year: 2005
  end-page: 1587
  ident: bib68
  article-title: Interrogating DNA repair in cancer risk assessment
  publication-title: Cancer Epidemiol. Biomarkers Prev.
– volume: 21
  start-page: 8232
  year: 2002
  end-page: 8239
  ident: bib54
  article-title: A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
  publication-title: Oncogene
– volume: 29
  start-page: 430
  year: 2001
  end-page: 438
  ident: bib25
  article-title: Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair
  publication-title: Nucl. Acids Res.
– volume: 51
  start-page: 5786
  year: 1991
  end-page: 5793
  ident: bib94
  article-title: Development and field-test validation of an assay for DNA repair in circulating human lymphocytes
  publication-title: Cancer Res.
– volume: 97
  start-page: 4156
  year: 2000
  end-page: 4161
  ident: bib47
  article-title: Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyadenine in mice
  publication-title: Proc. Natl. Acad. Sci. USA
– volume: 66
  start-page: 11683
  year: 2006
  end-page: 11689
  ident: bib72
  article-title: Reduced repair of the oxidative 8-oxoguanine DNA damage and the risk of head and neck cancer
  publication-title: Cancer Res.
– volume: 107
  start-page: 4223
  year: 2006
  end-page: 4233
  ident: bib6
  article-title: Molecular pathogenesis of Fanconi anemia: recent progress
  publication-title: Blood
– volume: 16
  start-page: 184
  year: 2007
  end-page: 191
  ident: bib103
  article-title: Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future
  publication-title: Eur. J. Cancer Prev.
– volume: 30
  start-page: 227
  year: 2002
  end-page: 232
  ident: bib5
  article-title: Inherited variants of MYH associated with somatic G:C
  publication-title: Nat. Genet.
– volume: 278
  start-page: 49679
  year: 2003
  end-page: 49684
  ident: bib29
  article-title: Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
  publication-title: J. Biol. Chem.
– volume: 476
  start-page: 73
  year: 2000
  end-page: 77
  ident: bib20
  article-title: Base excision repair of DNA in mammalian cells
  publication-title: FEBS Lett.
– volume: 6
  start-page: 481
  year: 2007
  end-page: 488
  ident: bib45
  article-title: Oxidative damage to purines in DNA: role of mammalian Ogg1
  publication-title: DNA Repair
– volume: 399
  start-page: 700
  year: 1999
  end-page: 704
  ident: bib8
  article-title: The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
  publication-title: Nature
– volume: 16
  start-page: 84
  year: 2007
  end-page: 91
  ident: bib67
  article-title: High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility
  publication-title: Cancer Epidemiol. Biomarkers Prev.
– volume: 96
  start-page: 51
  year: 2007
  end-page: 74
  ident: bib89
  article-title: Microarrays to identify new therapeutic strategies for cancer
  publication-title: Adv. Cancer Res.
– volume: 6
  start-page: 470
  year: 2007
  end-page: 480
  ident: bib28
  article-title: Oxidative DNA damage repair in mammalian cells: a new perspective
  publication-title: DNA Repair
– volume: 181
  start-page: 6210
  year: 1999
  end-page: 6213
  ident: bib34
  article-title: Functional expression of hMYH, a human homolog of the
  publication-title: J. Bacteriol.
– volume: 355
  start-page: 273
  year: 1992
  end-page: 275
  ident: bib11
  article-title: MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
  publication-title: Nature
– volume: 203
  start-page: 163
  year: 2002
  end-page: 177
  ident: bib92
  article-title: The comet assay. Principles, applications, and limitations
  publication-title: Methods Mol. Biol.
– volume: 162
  start-page: 925
  year: 2005
  end-page: 942
  ident: bib63
  article-title: Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review
  publication-title: Am. J. Epidemiol.
– volume: 258
  start-page: 605
  year: 1999
  end-page: 610
  ident: bib75
  article-title: Human MMH (OGG1) Type 1a protein is a major enzyme for repair of 8-hydroxyguanine lesions in human cells
  publication-title: Biochem. Biophys. Res. Commun.
– volume: 1
  start-page: 201
  year: 2005
  end-page: 205
  ident: bib77
  article-title: Repair of the oxidative DNA damage 8-oxoguanine as a biomarker for lung cancer risk
  publication-title: Cancer Biomarkers
– volume: 12
  start-page: 912
  year: 2002
  end-page: 918
  ident: bib43
  article-title: The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from oxidized dNTP pool
  publication-title: Curr. Biol.
– volume: 4
  start-page: 479
  year: 2003
  end-page: 483
  ident: bib18
  article-title: A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides
  publication-title: EMBO Rep.
– volume: 99
  start-page: 3523
  year: 2002
  end-page: 3528
  ident: bib27
  article-title: Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
  publication-title: Proc. Natl. Acad. Sci. USA
– start-page: 9
  year: 2005
  end-page: 15
  ident: bib87
  article-title: Biomarkers in molecular medicine: cancer detection and diagnosis
  publication-title: Biotechniques
– volume: 22
  start-page: 235
  year: 2007
  end-page: 243
  ident: bib97
  article-title: Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2
  publication-title: Mutagenesis
– volume: 6
  start-page: 274
  year: 2007
  end-page: 279
  ident: bib56
  article-title: MUTYH-associated polyposis – from defect in base excision repair to clinical genetic testing
  publication-title: DNA Repair
– volume: 67
  start-page: 6599
  year: 2007
  end-page: 6604
  ident: bib51
  article-title: MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis
  publication-title: Cancer Res.
– volume: 95
  start-page: 1312
  year: 2003
  end-page: 1319
  ident: bib69
  article-title: Reduced DNA repair activity for oxidative damage and the risk of lung cancer
  publication-title: J. Natl. Cancer Inst.
– volume: 266
  start-page: 1959
  year: 1994
  end-page: 1960
  ident: bib4
  article-title: Mismatch repair, genetic stability, and cancer
  publication-title: Science
– volume: 208
  start-page: 595
  year: 2006
  end-page: 606
  ident: bib88
  article-title: Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer
  publication-title: J. Pathol.
– volume: 31
  start-page: 10964
  year: 1992
  end-page: 10968
  ident: bib33
  article-title: A repair system for 8-oxo-7,8-dihydrodeoxyguanine
  publication-title: Biochemistry
– volume: 544
  start-page: 255
  year: 2003
  end-page: 271
  ident: bib80
  article-title: Linking exposure to environmental pollutants with biological effects
  publication-title: Mutat. Res.
– year: 1998
  ident: bib55
  article-title: The Genetic Basis of Human Cancer
– volume: 63
  start-page: 4351
  year: 2003
  end-page: 4357
  ident: bib71
  article-title: Decreased repair activities of 1,
  publication-title: Cancer Res.
– volume: 6
  start-page: 45
  year: 2007
  end-page: 60
  ident: bib73
  article-title: Development of an enzymatic DNA repair assay for molecular epidemiology studies: distribution of OGG activity in healthy individuals
  publication-title: DNA Repair
– volume: 92
  start-page: 1764
  year: 2000
  end-page: 1772
  ident: bib95
  article-title: Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study
  publication-title: J. Natl. Cancer Inst.
– volume: 16
  start-page: 6314
  year: 1997
  ident: 10.1016/j.canlet.2008.02.032_bib32
  article-title: Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
  publication-title: EMBO J.
  doi: 10.1093/emboj/16.20.6314
– volume: 476
  start-page: 73
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib20
  article-title: Base excision repair of DNA in mammalian cells
  publication-title: FEBS Lett.
  doi: 10.1016/S0014-5793(00)01674-4
– volume: 31
  start-page: 10964
  year: 1992
  ident: 10.1016/j.canlet.2008.02.032_bib33
  article-title: A repair system for 8-oxo-7,8-dihydrodeoxyguanine
  publication-title: Biochemistry
  doi: 10.1021/bi00160a004
– volume: 107
  start-page: 4223
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib6
  article-title: Molecular pathogenesis of Fanconi anemia: recent progress
  publication-title: Blood
  doi: 10.1182/blood-2005-10-4240
– volume: 27
  start-page: 3638
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib35
  article-title: Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/27.18.3638
– volume: 6
  start-page: 481
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib45
  article-title: Oxidative damage to purines in DNA: role of mammalian Ogg1
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.10.012
– volume: 383
  start-page: 915
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib81
  article-title: Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: potential role of lipid peroxidation, dietary fat and antioxidants
  publication-title: Biol. Chem.
  doi: 10.1515/BC.2002.098
– volume: 348
  start-page: 791
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib57
  article-title: Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa025283
– volume: 24
  start-page: 511
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib100
  article-title: Nutritional modulation of DNA repair in human intervention study
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/24.3.511
– volume: 67
  start-page: 3493
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib98
  article-title: Mutagen sensitivity: a genetic predisposition factor for cancer
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-4137
– volume: 63
  start-page: 902
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib49
  article-title: Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption
  publication-title: Cancer Res.
– volume: 278
  start-page: 49679
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib29
  article-title: Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M308658200
– volume: 67
  start-page: 6599
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib51
  article-title: MUTYH-null mice are susceptible to spontaneous and oxidative stress-induced intestinal tumorigenesis
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-4802
– volume: 314
  start-page: 155
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib84
  article-title: Gene-specific and mitochondrial repair of oxidative DNA damage
  publication-title: Methods Mol. Biol.
  doi: 10.1385/1-59259-973-7:155
– volume: 10
  start-page: 499
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib90
  article-title: Epitomics: global profiling of immune response to disease using protein microarrays
  publication-title: OMICS
  doi: 10.1089/omi.2006.10.499
– volume: 98
  start-page: 465
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib46
  article-title: Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis
  publication-title: Cancer Sci.
  doi: 10.1111/j.1349-7006.2007.00409.x
– volume: 37
  start-page: 271
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib91
  article-title: Gene expression profiling in breast cancer: towards individualising patient management
  publication-title: Pathology
  doi: 10.1080/00313020500169586
– volume: 355
  start-page: 273
  year: 1992
  ident: 10.1016/j.canlet.2008.02.032_bib11
  article-title: MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
  publication-title: Nature
  doi: 10.1038/355273a0
– volume: 486
  start-page: 207
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib61
  article-title: DNA repair activity of 8-oxoguanine DNA glycosylase I (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326
  publication-title: Mutat. Res.
  doi: 10.1016/S0921-8777(01)00096-9
– volume: 29
  start-page: 449
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib17
  article-title: Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/29.2.449
– volume: 258
  start-page: 605
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib75
  article-title: Human MMH (OGG1) Type 1a protein is a major enzyme for repair of 8-hydroxyguanine lesions in human cells
  publication-title: Biochem. Biophys. Res. Commun.
  doi: 10.1006/bbrc.1999.0649
– volume: 29
  start-page: 430
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib25
  article-title: Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/29.2.430
– volume: 356
  start-page: 2388
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib99
  article-title: Explaining the decrease in US deaths from coronary disease, 1980–2000
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMsa053935
– volume: 5
  start-page: 13
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib96
  article-title: Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2005.06.017
– volume: 411
  start-page: 366
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib2
  article-title: Genome maintenance mechanisms for preventing cancer
  publication-title: Nature
  doi: 10.1038/35077232
– volume: 21
  start-page: 8232
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib54
  article-title: A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1206027
– volume: 97
  start-page: 4156
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib47
  article-title: Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyadenine in mice
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.050404497
– volume: 6
  start-page: 274
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib56
  article-title: MUTYH-associated polyposis – from defect in base excision repair to clinical genetic testing
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.11.001
– volume: 325
  start-page: 1
  year: 1997
  ident: 10.1016/j.canlet.2008.02.032_bib24
  article-title: DNA glycosylases in the base excision repair of DNA
  publication-title: Biochem. J.
  doi: 10.1042/bj3250001
– volume: 208
  start-page: 595
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib88
  article-title: Array-based proteomics: mapping of protein circuitries for diagnostics, prognostics, and therapy guidance in cancer
  publication-title: J. Pathol.
  doi: 10.1002/path.1958
– volume: 30
  start-page: 227
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib5
  article-title: Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors
  publication-title: Nat. Genet.
  doi: 10.1038/ng828
– year: 1998
  ident: 10.1016/j.canlet.2008.02.032_bib55
– volume: 78
  start-page: 464
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib66
  article-title: Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/500848
– volume: 377
  start-page: 1
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib22
  article-title: The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis
  publication-title: Arch. Biochem. Biophys.
  doi: 10.1006/abbi.2000.1773
– volume: 3
  start-page: 129
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib76
  article-title: Novel molecular targets for risk identification: DNA repair enzyme activities
  publication-title: Cancer Biomarkers
  doi: 10.3233/CBM-2007-3303
– volume: 88
  start-page: 325
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib82
  article-title: DNA adducts as markers of exposure to carcinogens and risk of cancer
  publication-title: Int. J. Cancer
  doi: 10.1002/1097-0215(20001101)88:3<325::AID-IJC1>3.0.CO;2-K
– volume: 66
  start-page: 11683
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib72
  article-title: Reduced repair of the oxidative 8-oxoguanine DNA damage and the risk of head and neck cancer
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-2294
– volume: 266
  start-page: 1959
  year: 1994
  ident: 10.1016/j.canlet.2008.02.032_bib4
  article-title: Mismatch repair, genetic stability, and cancer
  publication-title: Science
  doi: 10.1126/science.7801122
– volume: 28
  start-page: 1355
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib39
  article-title: Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/28.6.1355
– start-page: 9
  issue: Suppl.
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib87
  article-title: Biomarkers in molecular medicine: cancer detection and diagnosis
  publication-title: Biotechniques
  doi: 10.2144/05384SU04
– volume: 17
  start-page: 415
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib86
  article-title: Applications of antibody array platforms
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2006.06.013
– volume: 551
  start-page: 79
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib102
  article-title: Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair
  publication-title: Mutat. Res.
  doi: 10.1016/j.mrfmmm.2004.02.018
– volume: 12
  start-page: 912
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib43
  article-title: The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from oxidized dNTP pool
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(02)00863-1
– volume: 34
  start-page: 1620
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib60
  article-title: Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/gkl060
– volume: 42
  start-page: 453
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib64
  article-title: No association between base excision repair gene polymorphism and risk of lung cancer
  publication-title: Biochem. Genet.
  doi: 10.1023/B:BIGI.0000043957.03420.7e
– volume: 95
  start-page: 1312
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib69
  article-title: Reduced DNA repair activity for oxidative damage and the risk of lung cancer
  publication-title: J. Natl. Cancer Inst.
  doi: 10.1093/jnci/djg033
– volume: 399
  start-page: 700
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib8
  article-title: The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
  publication-title: Nature
  doi: 10.1038/21447
– volume: 14
  start-page: 1585
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib68
  article-title: Interrogating DNA repair in cancer risk assessment
  publication-title: Cancer Epidemiol. Biomarkers Prev.
  doi: 10.1158/1055-9965.EPI-14-7-ED
– volume: 63
  start-page: 4899
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib70
  article-title: Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer
  publication-title: Cancer Res.
– volume: 51
  start-page: 5786
  year: 1991
  ident: 10.1016/j.canlet.2008.02.032_bib94
  article-title: Development and field-test validation of an assay for DNA repair in circulating human lymphocytes
  publication-title: Cancer Res.
– volume: 64
  start-page: 3096
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib50
  article-title: Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of K-Ras oncogene in lung tumors
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-03-3834
– volume: 16
  start-page: 184
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib103
  article-title: Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future
  publication-title: Eur. J. Cancer Prev.
  doi: 10.1097/01.cej.0000215612.98132.18
– volume: 33
  start-page: 5094
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib44
  article-title: 8-Oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/gki813
– volume: 21
  start-page: 361
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib83
  article-title: Oxyradicals and DNA damage
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/21.3.361
– volume: 94
  start-page: 9463
  year: 1997
  ident: 10.1016/j.canlet.2008.02.032_bib31
  article-title: In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.94.17.9463
– volume: 15
  start-page: 209
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib30
  article-title: AP endonuclease-independent DNA base excision repair in human cells
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2004.06.003
– volume: 63
  start-page: 4351
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib71
  article-title: Decreased repair activities of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in lung adenocarcinoma patients
  publication-title: Cancer Res.
– volume: 1
  start-page: 201
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib77
  article-title: Repair of the oxidative DNA damage 8-oxoguanine as a biomarker for lung cancer risk
  publication-title: Cancer Biomarkers
  doi: 10.3233/CBM-2005-12-308
– volume: 99
  start-page: 3523
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib27
  article-title: Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.062053799
– volume: 28
  start-page: 307
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib93
  article-title: DNA base excision repair as a biomarker in molecular epidemiology studies
  publication-title: Mol. Aspects Med.
  doi: 10.1016/j.mam.2007.05.005
– volume: 91
  start-page: 63
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib101
  article-title: Evidence that dietary supplementation with carotenoids and carotenoid-rich foods modulates the DNA damage:repair balance in human lymphocytes
  publication-title: Br. J. Nutr.
  doi: 10.1079/BJN20031001
– volume: 157
  start-page: 71
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib79
  article-title: Exposure biomarkers for the study of toxicological impact on carcinogenic processes
  publication-title: IARC Sci. Publ.
– volume: 510
  start-page: 81
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib37
  article-title: Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative lesion 8-oxoguanine in human cells
  publication-title: Mutat. Res.
  doi: 10.1016/S0027-5107(02)00254-3
– volume: 6
  start-page: 45
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib73
  article-title: Development of an enzymatic DNA repair assay for molecular epidemiology studies: distribution of OGG activity in healthy individuals
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.08.003
– volume: 403
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib23
  article-title: Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
  publication-title: Nature
  doi: 10.1038/35002510
– volume: 4
  start-page: 439
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib42
  article-title: MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80346-9
– volume: 9
  start-page: 246
  year: 1993
  ident: 10.1016/j.canlet.2008.02.032_bib38
  article-title: Mutagenesis by 8-oxoguanine: an enemy within
  publication-title: Trends Genet.
  doi: 10.1016/0168-9525(93)90089-Z
– volume: 349
  start-page: 431
  year: 1991
  ident: 10.1016/j.canlet.2008.02.032_bib13
  article-title: Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
  publication-title: Nature
  doi: 10.1038/349431a0
– volume: 96
  start-page: 51
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib89
  article-title: Microarrays to identify new therapeutic strategies for cancer
  publication-title: Adv. Cancer Res.
  doi: 10.1016/S0065-230X(06)96003-5
– volume: 33
  start-page: 1813
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib62
  article-title: Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harboring the hOGG1-Cys326 polymorphic variant
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/gki325
– volume: 25
  start-page: 4305
  year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib78
  article-title: New functions of XPC in the protection of human skin cells from oxidative damage
  publication-title: EMBO J.
  doi: 10.1038/sj.emboj.7601277
– volume: 274
  start-page: 18201
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib16
  article-title: The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.274.26.18201
– volume: 22
  start-page: 235
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib97
  article-title: Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2
  publication-title: Mutagenesis
  doi: 10.1093/mutage/gem008
– volume: 90
  start-page: 1122
  year: 1993
  ident: 10.1016/j.canlet.2008.02.032_bib36
  article-title: Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted GC to TA transversions in simian kidney cells
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.90.3.1122
– volume: 27
  start-page: 4001
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib59
  article-title: Excision of oxidatively damaged DNA bases by the human alpha-hOGG1 protein and the polymorphic alpha-hOGG1-(Ser326/Cys326) protein which is frequently found in human populations
  publication-title: Nucl. Acids Res.
  doi: 10.1093/nar/27.20.4001
– volume: 7
  start-page: 1849
  year: 1986
  ident: 10.1016/j.canlet.2008.02.032_bib10
  article-title: Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/7.11.1849
– volume: 98
  start-page: 11456
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib52
  article-title: Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.191086798
– volume: 60
  start-page: 2064
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib40
  article-title: Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis
  publication-title: Cell. Mol. Life Sci.
  doi: 10.1007/s00018-003-3053-4
– volume: 96
  start-page: 13,300
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib48
  article-title: Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.96.23.13300
– volume: 6
  start-page: 317
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib26
  article-title: Mechanism of interaction between human 8-oxoguanine-DNA glycosylase and AP endonuclease
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.10.022
– volume: 203
  start-page: 163
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib92
  article-title: The comet assay. Principles, applications, and limitations
  publication-title: Methods Mol. Biol.
– volume: 10
  start-page: 789
  year: 2004
  ident: 10.1016/j.canlet.2008.02.032_bib3
  article-title: Cancer genes and the pathways they control
  publication-title: Nat. Med.
  doi: 10.1038/nm1087
– volume: 327
  start-page: 77
  year: 1987
  ident: 10.1016/j.canlet.2008.02.032_bib12
  article-title: Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
  publication-title: Nature
  doi: 10.1038/327077a0
– volume: 6
  start-page: 470
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib28
  article-title: Oxidative DNA damage repair in mammalian cells: a new perspective
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.10.011
– volume: 1
  start-page: 22
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib7
  article-title: How nucleotide excision repair protects against cancer
  publication-title: Nat. Rev. Cancer
  doi: 10.1038/35094000
– volume: 285
  start-page: 263
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib9
  article-title: hRAD30 mutations in the variant form of xeroderma pigmentosum
  publication-title: Science
  doi: 10.1126/science.285.5425.263
– volume: 411
  start-page: 390
  year: 2001
  ident: 10.1016/j.canlet.2008.02.032_bib58
  article-title: Cancer epidemiology in the last century and the next decade
  publication-title: Nature
  doi: 10.1038/35077256
– volume: 92
  start-page: 1764
  year: 2000
  ident: 10.1016/j.canlet.2008.02.032_bib95
  article-title: Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study
  publication-title: J. Natl. Cancer Inst.
  doi: 10.1093/jnci/92.21.1764
– volume: 24
  start-page: 485
  year: 1994
  ident: 10.1016/j.canlet.2008.02.032_bib15
  article-title: Genomic structure and chromosome location of the human MutT homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to G:C transversion
  publication-title: Genomics
  doi: 10.1006/geno.1994.1657
– volume: 29
  start-page: 551
  year: 1998
  ident: 10.1016/j.canlet.2008.02.032_bib85
  article-title: Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry
  publication-title: Free Radic. Res.
  doi: 10.1080/10715769800300591
– volume: 114
  start-page: 730
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib65
  article-title: Association of amino acid substitution polymorphism in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk
  publication-title: Int. J. Cancer
  doi: 10.1002/ijc.20790
– volume: 33
  start-page: 4695
  year: 1994
  ident: 10.1016/j.canlet.2008.02.032_bib14
  article-title: DNA replication fidelity with 8-oxodeoxyguanosine triphosphate
  publication-title: Biochemistry
  doi: 10.1021/bi00181a029
– volume: 254
  start-page: 1
  year: 1991
  ident: 10.1016/j.canlet.2008.02.032_bib74
  article-title: An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA
  publication-title: Mutat. Res.
  doi: 10.1016/0921-8777(91)90035-N
– volume: 4
  start-page: 479
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib18
  article-title: A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides
  publication-title: EMBO Rep.
  doi: 10.1038/sj.embor.embor838
– volume: 181
  start-page: 6210
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib34
  article-title: Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein
  publication-title: J. Bacteriol.
  doi: 10.1128/JB.181.19.6210-6213.1999
– volume: 162
  start-page: 925
  year: 2005
  ident: 10.1016/j.canlet.2008.02.032_bib63
  article-title: Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review
  publication-title: Am. J. Epidemiol.
  doi: 10.1093/aje/kwi318
– volume: 16
  start-page: 84
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib67
  article-title: High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility
  publication-title: Cancer Epidemiol. Biomarkers Prev.
  doi: 10.1158/1055-9965.EPI-06-0712
– year: 2006
  ident: 10.1016/j.canlet.2008.02.032_bib1
– volume: 27
  start-page: 1365
  year: 1999
  ident: 10.1016/j.canlet.2008.02.032_bib53
  article-title: Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells
  publication-title: Nucl. Acids. Res.
  doi: 10.1093/nar/27.5.1365
– volume: 6
  start-page: 398
  year: 2007
  ident: 10.1016/j.canlet.2008.02.032_bib21
  article-title: Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways
  publication-title: DNA Repair
  doi: 10.1016/j.dnarep.2006.10.008
– volume: 20
  start-page: 391
  year: 1995
  ident: 10.1016/j.canlet.2008.02.032_bib19
  article-title: The base excision repair pathway
  publication-title: Trends Biochem. Sci.
  doi: 10.1016/S0968-0004(00)89086-6
– volume: 12
  start-page: 3350339
  year: 2002
  ident: 10.1016/j.canlet.2008.02.032_bib41
  article-title: Replication-associated repair of adenine:8-oxoguanine mispairs by MYH
  publication-title: Curr. Biol.
  doi: 10.1016/S0960-9822(02)00686-3
– volume: 544
  start-page: 255
  year: 2003
  ident: 10.1016/j.canlet.2008.02.032_bib80
  article-title: Linking exposure to environmental pollutants with biological effects
  publication-title: Mutat. Res.
  doi: 10.1016/j.mrrev.2003.06.010
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Snippet Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of...
Abstract Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to...
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SubjectTerms 8-Oxoguanine
Animals
Comet Assay
DNA Damage
DNA Glycosylases - metabolism
DNA Repair
DNA repair enzymatic activity
Early detection
Early Diagnosis
Functional DNA repair assay
Guanine - analogs & derivatives
Hematology, Oncology and Palliative Medicine
Humans
Medical research
Mice
Mutation
Neoplasms - diagnosis
Neoplasms - enzymology
Neoplasms - genetics
OGG1
Oxidative stress
Risk Assessment
Smoking - adverse effects
Title DNA repair of oxidative DNA damage in human carcinogenesis: Potential application for cancer risk assessment and prevention
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https://dx.doi.org/10.1016/j.canlet.2008.02.032
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https://www.proquest.com/docview/71621399
https://pubmed.ncbi.nlm.nih.gov/PMC2563153
Volume 266
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