Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of B-cells in infections caused by intracellular bacteria is fragmentary and contradictory. We therefore analysed the phenotypical and functiona...

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Veröffentlicht in:PLoS pathogens Jg. 12; H. 6; S. e1005687
Hauptverfasser: Joosten, Simone A., van Meijgaarden, Krista E., del Nonno, Franca, Baiocchini, Andrea, Petrone, Linda, Vanini, Valentina, Smits, Hermelijn H., Palmieri, Fabrizio, Goletti, Delia, Ottenhoff, Tom H. M.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Public Library of Science 01.06.2016
Public Library of Science (PLoS)
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ISSN:1553-7374, 1553-7366, 1553-7374
Online-Zugang:Volltext
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