Humoral Immune Responses of Dengue Fever Patients Using Epitope-Specific Serotype-2 Virus-Like Particle Antigens

Dengue virus (DENV) is a serious mosquito-borne pathogen causing significant global disease burden, either as classic dengue fever (DF) or in its most severe manifestation dengue hemorrhagic fever (DHF). Nearly half of the world's population is at risk of dengue disease and there are estimated...

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Bibliographic Details
Published in:	PloS one Vol. 4; no. 4; p. e4991
Main Authors:	Crill, Wayne D., Hughes, Holly R., Delorey, Mark J., Chang, Gwong-Jen J.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.04.2009 Public Library of Science (PLoS)
Subjects:	Amino Acid Sequence Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Antibodies, Viral - biosynthesis Antibodies, Viral - chemistry Antibodies, Viral - immunology Antibody response Antigenic determinants Antigens Antigens, Viral - chemistry Antigens, Viral - immunology Antiviral agents Aquatic insects Base Sequence Biosynthesis Dengue - immunology Dengue fever Dengue hemorrhagic fever Dengue virus Disease control Disease prevention DNA Primers Encephalitis Enzymes Epidemics Epitope Mapping Epitopes Epitopes - chemistry Epitopes - immunology Fever Health aspects Health risks Health services Hemorrhagic fevers Human behavior Humans Immune response Immune response (humoral) Immunoglobulin G Immunoglobulin M Immunoglobulins Immunology Immunology/Immune Response Infection Infections Infectious diseases Infectious Diseases/Viral Infections Medical research Microbiology/Medical Microbiology Models, Molecular Molecular Sequence Data Mosquitoes Neutralization Pathogenicity Pathogens Peptides Populations Protein Conformation Proteins Public health Sequence Homology, Amino Acid Vaccination Vaccine development Vaccines Vector-borne diseases Vectors Vectors (Biology) Viral diseases Viral envelope proteins Virology Virology/Emerging Viral Diseases Virology/Host Antiviral Responses Viruses West Nile virus United States > US Colorado
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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