Course of Chronic Trypanosoma cruzi Infection after Treatment Based on Parasitological and Serological Tests: A Systematic Review of Follow-Up Studies

Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi (T. cruzi). It is endemic in Latin American countries outside the Caribbean. The current criterion for cure in the chronic phase of the disease is the negativization of at least two serological tests such as enzyme-linked immunos...

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Bibliographic Details
Published in:	PloS one Vol. 10; no. 10; p. e0139363
Main Authors:	Sguassero, Yanina, Cuesta, Cristina B., Roberts, Karen N., Hicks, Elizabeth, Comandé, Daniel, Ciapponi, Agustín, Sosa-Estani, Sergio
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 05.10.2015 Public Library of Science (PLoS)
Subjects:	Adult Adults Antibodies, Protozoan - blood Antigens Assaying Benznidazole Bias Blood & organ donations Care and treatment Causes of Chagas disease Chagas Disease - drug therapy Chagas Disease - epidemiology Chagas Disease - immunology Chagas Disease - parasitology Child Children Chronic Disease Chronic infection Cohort Studies Congenital diseases Diagnosis Disease Disease Progression DNA, Protozoan - blood Enzyme-Linked Immunosorbent Assay Fluorescent Antibody Technique, Indirect Follow-Up Studies Hemagglutination Hemagglutination Tests Heterogeneity Humans Immunofluorescence Indirect hemagglutination Infections Infectious diseases Laboratories Nifurtimox Nifurtimox - therapeutic use Nitroimidazoles - therapeutic use Parasitemia Parasitemia - drug therapy Parasitemia - epidemiology Parasitemia - immunology Parasitemia - parasitology Parasites Physiological aspects Polymerase chain reaction Prospero protein Protozoa Randomized Controlled Trials as Topic Reviews Risk assessment Serological tests Subgroups Systematic review Treatment Failure Trypanocidal Agents - therapeutic use Trypanosoma cruzi Trypanosoma cruzi - immunology Vector-borne diseases Xenodiagnosis Argentina United States > US
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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