Multiple Sclerosis Susceptibility Genes: Associations with Relapse Severity and Recovery

Patients with early multiple sclerosis (MS) have stereotyped attack severity and recovery. We sought to determine if polymorphisms in MS susceptibility genes are associated with these attack features or with the risk of a second attack. 503 white subjects evaluated within a year of MS onset were inc...

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Vydáno v:	PloS one Ročník 8; číslo 10; s. e75416
Hlavní autoři:	Mowry, Ellen M., Carey, Robert F., Blasco, Maria R., Pelletier, Jean, Duquette, Pierre, Villoslada, Pablo, Malikova, Irina, Roger, Elaine, Kinkel, R. Phillip, McDonald, Jamie, Bacchetti, Peter, Waubant, Emmanuelle
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 09.10.2013 Public Library of Science (PLoS)
Témata:	Adult Antigens, CD - genetics Antigens, Differentiation, T-Lymphocyte - genetics Brain research CD6 antigen Clinical trials Disease susceptibility Drb1 protein Female Gene polymorphism Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease - genetics Genetics Glypicans - genetics Histocompatibility antigen HLA HLA antigens HLA-DRB1 Chains - genetics Humans Interferon Interleukin 7 receptors Male Multiple sclerosis Multiple Sclerosis - genetics Multiple Sclerosis - pathology Neurology Neurosciences NMR Nuclear magnetic resonance Pathogenesis Patients Phosphoproteins - genetics Polymorphism Polymorphism, Single Nucleotide - genetics Receptors, Tumor Necrosis Factor, Type I - genetics Recovery Recovery (Medical) RGS Proteins - genetics Young Adult Canada San Francisco California United States > US Montreal Quebec Canada California France Spain
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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