Efficient protein production inspired by how spiders make silk

Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge concentrations by sequestering their aggregation-prone regions in micellar structures, where the ver...

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Veröffentlicht in:Nature communications Jg. 8; H. 1; S. 15504 - 15
Hauptverfasser: Kronqvist, Nina, Sarr, Médoune, Lindqvist, Anton, Nordling, Kerstin, Otikovs, Martins, Venturi, Luca, Pioselli, Barbara, Purhonen, Pasi, Landreh, Michael, Biverstål, Henrik, Toleikis, Zigmantas, Sjöberg, Lisa, Robinson, Carol V., Pelizzi, Nicola, Jörnvall, Hans, Hebert, Hans, Jaudzems, Kristaps, Curstedt, Tore, Rising, Anna, Johansson, Jan
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 23.05.2017
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ISSN:2041-1723, 2041-1723
Online-Zugang:Volltext
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