A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles amongst Different Primary Murine Macrophages

Chemotaxis assays are an invaluable tool for studying the biological activity of inflammatory mediators such as CC chemokines, which have been implicated in a wide range of chronic inflammatory diseases. Conventional chemotaxis systems such as the modified Boyden chamber are limited in terms of the...

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Bibliographic Details
Published in:	PloS one Vol. 8; no. 3; p. e58744
Main Authors:	Iqbal, Asif J., Regan-Komito, Daniel, Christou, Ivy, White, Gemma E., McNeill, Eileen, Kenyon, Amy, Taylor, Lewis, Kapellos, Theodore S., Fisher, Edward A., Channon, Keith M., Greaves, David R.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 14.03.2013 Public Library of Science (PLoS)
Subjects:	Actin Analysis Animals Antigens Assaying Biological activity Biology Bone marrow Bone Marrow Cells - cytology Boyden chamber CC chemokines CD14 antigen Cell migration Chemokines Chemokines, CC - pharmacology Chemokinesis Chemotaxis Chemotaxis - drug effects Cytochalasin D Cytokines Cytoskeleton Cytoskeleton - drug effects Cytoskeleton - metabolism Ethics Gene expression GTP-Binding Protein alpha Subunits, Gi-Go - metabolism Humans Inflammation Inflammatory diseases Laboratories Macrophages Macrophages - cytology Male Medicine Mice Mice, Inbred C57BL Monocyte chemoattractant protein 1 Monocytes Monocytes - cytology Monocytes - drug effects Pathology Penicillin Pertussis Pertussis toxin Populations Proteins Real time Signal transduction Signal Transduction - drug effects Signaling Time Factors Toxins New York United States > US
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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