Levels of Protein C and Soluble Thrombomodulin in Critically Ill Patients with Acute Kidney Injury: A Multicenter Prospective Observational Study

Endothelial dysfunction contributes to the development of acute kidney injury (AKI) in animal models of ischemia reperfusion injury and sepsis. There are limited data on markers of endothelial dysfunction in human AKI. We hypothesized that Protein C (PC) and soluble thrombomodulin (sTM) levels could...

Full description

Saved in:

Bibliographic Details
Published in:	PloS one Vol. 10; no. 3; p. e0120770
Main Authors:	Bouchard, Josée, Malhotra, Rakesh, Shah, Shamik, Kao, Yu-Ting, Vaida, Florin, Gupta, Akanksha, Berg, David T., Grinnell, Brian W., Stofan, Brenda, Tolwani, Ashita J., Mehta, Ravindra L.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 19.03.2015 Public Library of Science (PLoS)
Subjects:	Acute Kidney Injury - blood Acute Kidney Injury - diagnosis Acute Kidney Injury - mortality Animal models Anticoagulants Bioinformatics Biomarkers Biomarkers - blood Biotechnology Cell cycle Creatinine Critical care Critical Illness Cystatin Cystatin C Family medical history Fatty acid-binding protein Fatty acids Female Gelatinase Hospitals Humans Hypertension Injury prevention Intensive care Ischemia Kidney diseases Kidneys Laboratories Lipocalin Liver Male Markers Mathematical models Medical research Medicine Middle Aged Mortality Nephrology Observational studies Patients Prognosis Prospective Studies Protein binding Protein C Protein C - metabolism Proteins Recovery Reperfusion Sepsis Short term memory Solubility Studies Thrombomodulin Thrombomodulin - blood Thrombomodulin - chemistry Urine California Alabama United States > US Indianapolis Indiana
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!