A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction

Dysregulation of the stress response is implicated in drug addiction; therefore, polymorphisms in stress-related genes may be involved in this disease. An analysis was performed to identify associations between variants in 11 stress-related genes, selected a priori, and heroin addiction. Two discove...

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Bibliographic Details
Published in:	PloS one Vol. 13; no. 6; p. e0199951
Main Authors:	Levran, Orna, Correa da Rosa, Joel, Randesi, Matthew, Rotrosen, John, Adelson, Miriam, Kreek, Mary Jeanne
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 28.06.2018 Public Library of Science (PLoS)
Subjects:	Addictions Adelson, Sheldon Alcohol Alcoholic beverages Anxiety Bioinformatics Biology Biology and life sciences Care and treatment Development and progression Drug abuse Drug addiction Filtration Gene expression Genes Genetic aspects Genomes Health aspects Heroin Heroin habit Laboratories Medicine and Health Sciences Methadone Minority & ethnic groups Narcotics Non-coding RNA Permutations Physical Sciences Pituitary Post traumatic stress disorder Posttraumatic stress disorder Principal components analysis Psychiatry Quantitative trait loci Ribonucleic acid RNA Single nucleotide polymorphisms Single-nucleotide polymorphism Social Sciences Stress response Stresses Studies Substance abuse treatment New York United States > US Las Vegas Nevada
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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