BMP Signaling and the Maintenance of Primordial Germ Cell Identity in Drosophila Embryos

The specification of primordial germ cells (PGCs) and subsequent maintenance of germ-line identity in Drosophila embryos has long been thought to occur solely under the control of cell-autonomous factors deposited in the posterior pole plasm during oogenesis. However, here we document a novel role f...

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Veröffentlicht in:	PloS one Jg. 9; H. 2; S. e88847
Hauptverfasser:	Deshpande, Girish, Willis, Elinor, Chatterjee, Sandip, Fernandez, Robert, Dias, Kristen, Schedl, Paul
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 14.02.2014 Public Library of Science (PLoS)
Schlagworte:	Animals Autocrine Communication Biology Bone morphogenetic proteins Bone Morphogenetic Proteins - metabolism Cell division Cell Nucleus - metabolism Cell signaling Coalescence Coalescing Down-Regulation Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - embryology Drosophila Proteins - metabolism Embryo, Nonmammalian - cytology Embryo, Nonmammalian - metabolism Embryonic Development Embryos Gene expression Germ cells Germ Cells - cytology Germ Cells - metabolism Homology Insects Maintenance Molecular biology Oogenesis Phosphorylation Signal Transduction Signaling Stem cells
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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