Health Effects of Lesion Localization in Multiple Sclerosis: Spatial Registration and Confounding Adjustment

Brain lesion localization in multiple sclerosis (MS) is thought to be associated with the type and severity of adverse health effects. However, several factors hinder statistical analyses of such associations using large MRI datasets: 1) spatial registration algorithms developed for healthy individu...

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Veröffentlicht in:	PloS one Jg. 9; H. 9; S. e107263
Hauptverfasser:	Eloyan, Ani, Shou, Haochang, Shinohara, Russell T., Sweeney, Elizabeth M., Nebel, Mary Beth, Cuzzocreo, Jennifer L., Calabresi, Peter A., Reich, Daniel S., Lindquist, Martin A., Crainiceanu, Ciprian M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 18.09.2014 Public Library of Science (PLoS)
Schlagworte:	Adult Aged Algorithms Autoimmune diseases Biology and Life Sciences Brain Brain - diagnostic imaging Brain - pathology Brain damage Brain research Data Interpretation, Statistical Disability Epidemiology Female Health aspects Health risks Humans Image Interpretation, Computer-Assisted - methods Image Processing, Computer-Assisted Lesions Localization Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine and Health Sciences Middle Aged Multiple sclerosis Multiple Sclerosis - pathology Neurological disorders Neurology NMR Nuclear magnetic resonance Physical Sciences Population (statistical) Public health Radiography Registration Regression analysis Spatial distribution Statistical analysis Studies Young Adult
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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