The Lung Microbiome of Ugandan HIV-Infected Pneumonia Patients Is Compositionally and Functionally Distinct from That of San Franciscan Patients

Sub-Saharan Africa represents 69% of the total number of individuals living with HIV infection worldwide and 72% of AIDS deaths globally. Pulmonary infection is a common and frequently fatal complication, though little is known regarding the lower airway microbiome composition of this population. Ou...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 4; p. e95726
Main Authors:	Iwai, Shoko, Huang, Delphine, Fong, Serena, Jarlsberg, Leah G., Worodria, William, Yoo, Samuel, Cattamanchi, Adithya, Davis, J. Lucian, Kaswabuli, Sylvia, Segal, Mark, Huang, Laurence, Lynch, Susan V.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.04.2014 Public Library of Science (PLoS)
Subjects:	Acquired immune deficiency syndrome Adult Aged Aged, 80 and over AIDS AIDS (Disease) Alveoli Bacteria Bacterial pneumonia Biology and Life Sciences Bronchus Care and treatment Clostridium Coding Control Critical care Demographic variables Demographics Developed countries Diagnosis Drug therapy Epidemiology Ethics Female Gastroenterology Health aspects Health care HIV HIV Infections - microbiology HIV patients Hospitals Human immunodeficiency virus Humans Immunology Infections Lung - microbiology Lungs Male Matrix metalloproteinase Medicine Medicine and Health Sciences Metalloproteinase Microbiota Microbiota - genetics Microbiota - physiology Middle Aged Patients Pneumonia Pneumonia - microbiology Pseudomonas aeruginosa Pseudomonas aeruginosa - pathogenicity Research and Analysis Methods Respiratory tract Ribonucleic acid RNA rRNA 16S San Francisco Social Sciences Sulfur Sulfur-reducing bacteria Tumor necrosis factor-α Uganda Young Adult San Francisco Uganda California San Francisco California United States > US Kampala Uganda
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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