Metabolomic Derangements Are Associated with Mortality in Critically Ill Adult Patients

To identify metabolomic biomarkers predictive of Intensive Care Unit (ICU) mortality in adults. Comprehensive metabolomic profiling of plasma at ICU admission to identify biomarkers associated with mortality has recently become feasible. We performed metabolomic profiling of plasma from 90 ICU subje...

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Vydáno v:	PloS one Ročník 9; číslo 1; s. e87538
Hlavní autoři:	Rogers, Angela J., McGeachie, Michael, Baron, Rebecca M., Gazourian, Lee, Haspel, Jeffrey A., Nakahira, Kiichi, Fredenburgh, Laura E., Hunninghake, Gary M., Raby, Benjamin A., Matthay, Michael A., Otero, Ronny M., Fowler, Vance G., Rivers, Emanuel P., Woods, Christopher W., Kingsmore, Stephen, Langley, Ray J., Choi, Augustine M. K.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 30.01.2014 Public Library of Science (PLoS)
Témata:	Adults Aged Amino acids Analysis Bayes Theorem Bayesian analysis Biology Biomarkers Biomarkers - metabolism Carbohydrates Community-Acquired Infections - metabolism Community-Acquired Infections - mortality Critical care Critical Illness - mortality Emergency medical care Enrollments Female Gene expression Genomes Genotype & phenotype Hormones Hospital Mortality Hospital patients Hospitals Humans Identification methods Infection Intensive care Intensive Care Units Lactates Lactic acid Lipid metabolism Lipids Male Mathematics Medicine Metabolism Metabolites Metabolomics Metabolomics - methods Middle Aged Mortality Nucleotides Patient outcomes Patients Prognosis Replication Sepsis Sepsis - metabolism Sepsis - mortality Sucrose Sugar New York California United States > US New Mexico Massachusetts
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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