The Network Architecture of the Saccharomyces cerevisiae Genome

We propose a network-based approach for surmising the spatial organization of genomes from high-throughput interaction data. Our strategy is based on methods for inferring architectural features of networks. Specifically, we employ a community detection algorithm to partition networks of genomic int...

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Bibliographic Details
Published in:	PloS one Vol. 8; no. 12; p. e81972
Main Authors:	Hoang, Stephen A., Bekiranov, Stefan
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 09.12.2013 Public Library of Science (PLoS)
Subjects:	Algorithms Analysis Binding sites Biochemistry Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Centromere - chemistry Centromeres Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Clustering Cohesin Cohesins Communities Conformation Datasets Deoxyribonucleic acid DNA Gene expression Gene Regulatory Networks Genetic aspects Genome, Fungal Genomes Genomics Kinases Network analysis Networks Partitions Principles Protein Interaction Mapping RNA, Transfer - genetics RNA, Transfer - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Telomerase Telomere - chemistry Telomeres Yeast United States > US Virginia
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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