Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling

Existing normative flow cytometry data have several limitations including small sample sizes, incompletely described study populations, variable flow cytometry methodology, and limited depth for defining lymphocyte subpopulations. To overcome these issues, we defined high-dimensional flow cytometry...

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Bibliographic Details
Published in:	PloS one Vol. 14; no. 12; p. e0225512
Main Authors:	Yi, John S., Rosa-Bray, Marilyn, Staats, Janet, Zakroysky, Pearl, Chan, Cliburn, Russo, Melissa A., Dumbauld, Chelsae, White, Scott, Gierman, Todd, Weinhold, Kent J., Guptill, Jeffrey T.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 11.12.2019 Public Library of Science (PLoS)
Subjects:	Adolescent Adult Age Factors Aged Antigens B cells Biology and Life Sciences Cell activation Cell Separation - methods Cell Separation - standards Consortia Continental Population Groups Datasets Disease Downloading Family medical history Female Flow cytometry Flow Cytometry - methods Flow Cytometry - standards Healthy Volunteers Humans Immune system Immunity, Cellular - physiology Immunology Laboratories Laboratory tests Leukocytes (mononuclear) Leukocytes, Mononuclear - immunology Lymphocyte Subsets - immunology Lymphocytes Lymphocytes B Lymphocytes T Male Medicine Medicine and Health Sciences Methods Middle Aged People and places Peripheral blood mononuclear cells Plasma Population studies Reference Values Research and Analysis Methods Standardization Subpopulations Surgery T cells Vaccines Visualization (Computer) Web site management software Young Adult United States > US
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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