Using First Passage Statistics to Extract Environmentally Dependent Amino Acid Correlations

In this work, we study the first passage statistics of amino acid primary sequences, that is the probability of observing an amino acid for the first time at a certain number of residues away from a fixed amino acid. By using this rich mathematical framework, we are able to capture the background di...

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Bibliographic Details
Published in:	PloS one Vol. 9; no. 7; p. e101665
Main Authors:	Greenbaum, Benjamin D., Kumar, Pradeep, Libchaber, Albert
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 07.07.2014 Public Library of Science (PLoS)
Subjects:	Amino Acids Arginine Biology Biology and Life Sciences Chemical bonds Computational Biology - methods Correlation Correlation analysis Cysteine Ecosystem Environment Environmental statistics Genomes Genomics Glutamic acid High temperature High temperature environments Markov analysis Natural selection Organisms Phylogeny Physical Sciences Physics Physiochemistry Probability Proteins Residues Sequences Statistics Studies Temperature Temperature dependence Thermal stability New York United States > US New Jersey
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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