Comprehensive proteomic quantification of bladder stone progression in a cystinuric mouse model using data-independent acquisitions

Cystinuria is one of various disorders that cause biomineralization in the urinary system, including bladder stone formation in humans. It is most prevalent in children and adolescents and more aggressive in males. There is no cure, and only limited disease management techniques help to solubilize t...

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Veröffentlicht in:	PloS one Jg. 17; H. 6; S. e0250137
Hauptverfasser:	Rose, Jacob, Basisty, Nathan, Zee, Tiffany, Wehrfritz, Cameron, Bose, Neelanjan, Desprez, Pierre-Yves, Kapahi, Pankaj, Stoller, Marshall, Schilling, Birgit
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 30.06.2022 Public Library of Science (PLoS)
Schlagworte:	Acids Aminoaciduria, Renal Analysis Animals Biology and Life Sciences Bladder Children Coagulation Computed tomography Cystine - metabolism Cystinuria Data acquisition Degranulation Depth profiling Developmental stages Diagnosis Genetic aspects Male Mass spectrometry Medicine and Health Sciences Mice Mineralization Peptides Proteins Proteomes Proteomics Research and Analysis Methods Ribosomal proteins Scientific imaging Solvents Urinary Bladder Calculi - diagnostic imaging Urine X-Ray Microtomography United States
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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