Determinants of Glycemic Control among Insulin Treated Diabetic Patients in Southwest Ethiopia: Hospital Based Cross Sectional Study

Good glycemic control reduces the risk of diabetic complications. Despite this, achieving good glycemic control remains a challenge in diabetic patients. The objective of this study is to identify determinants of glycemic control among insulin treated diabetic patients at Jimma University Hospital,...

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Veröffentlicht in:PloS one Jg. 8; H. 4; S. e61759
Hauptverfasser: Angamo, Mulugeta Tarekegn, Melese, Belete Habte, Ayen, Wubeante Yenet
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Public Library of Science 19.04.2013
Public Library of Science (PLoS)
Schlagworte:
Activities of daily living
Adolescent
Adult
Aged
Aged, 80 and over
Analysis
Blood glucose
Body weight
Care and treatment
Chronic illnesses
Complications
Cross-Sectional Studies
Data collection
Demography
Determinants
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 1 - drug therapy
Diabetes Mellitus, Type 2 - drug therapy
Diabetes therapy
Diabetics
Diet
Drug stores
Ethiopia
Female
Glucose
Health care
Hospitals
Hospitals, University
Humans
Hyperglycemia
Hypoglycemic Agents - therapeutic use
Insulin
Insulin - therapeutic use
Logistic Models
Male
Males
Medical research
Medicine
Middle Aged
Multivariate Analysis
Patients
Pharmacy
Regression analysis
Risk management
Risk reduction
Signs and symptoms
Sociodemographics
Sugar
Young Adult
Ethiopia
United States > US
ISSN:1932-6203, 1932-6203
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Zusammenfassung:Good glycemic control reduces the risk of diabetic complications. Despite this, achieving good glycemic control remains a challenge in diabetic patients. The objective of this study is to identify determinants of glycemic control among insulin treated diabetic patients at Jimma University Hospital, Southwest Ethiopia. Hospital-based cross-sectional study was conducted on systematically sampled 284 insulin-treated diabetic patients with a regular follow up. Data was collected by interviewing patients during hospital visits and reviewing respective databases of September 2010 to December 2011. Data collection took place from February 20 to May 20, 2012. Poor glycemic control was defined as fasting blood sugar (FBS) ≥126 mg/dL. Binary logistic regression analysis was conducted to identify predictors of poor glycemic control. Patients had a mean age of 41.37 (±15.08) years, 58.5% were males, the mean duration of insulin treatment was 4.9 (±5.1) years, 18.3% achieved good glycemic control (FBS≤126 mg/dL), 95% self-reported repeated use of disposable insulin syringe-needle and 48% correctly rotating insulin injection sites. Most (83.1%) of study participants had one or more complications. On multivariable logistic regression analyses, body weight of >70 Kg (AOR = 0.21; P<0.001), total daily dose of insulin ≤35 IU/day (AOR = 0.26; P<0.001), total daily dose variation without checking glycemic level (AOR = 3.39; P = 0.020), knowledge deficit about signs and symptoms of hyperglycemia (AOR = 3.60; P = 0.004), and non-adherence to dietary management (AOR = 0.35; P = 0.005) were independent predictors of poor glycemic control. The proportion of patients with poor glycemic control was high, which resulted in the development of one or more complications regardless of duration on insulin treatment. Hence, appropriate management of patients focusing on the relevant associated factors and independent predictors of poor glycemic control would be of great benefit in glycemic control.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Competing Interests: The authors declare that they have no competing interests.
Conceived and designed the experiments: MTA BHM WYA. Performed the experiments: MTA BHM WYA. Analyzed the data: MTA BHM WYA. Contributed reagents/materials/analysis tools: MTA BHM WYA. Wrote the paper: MTA BHM WYA.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0061759