Genetically regulated gene expression and proteins revealed discordant effects

Although gene-expression (GE) and protein levels are typically strongly genetically regulated, their correlation is known to be low. Here we investigate this phenomenon by focusing on the genetic background of this correlation in order to understand the similarities and differences in the genetic re...

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Bibliographic Details
Published in:	PloS one Vol. 17; no. 5; p. e0268815
Main Authors:	Pott, Janne, Garcia, Tarcyane, Hauck, Stefanie M., Petrera, Agnese, Wirkner, Kerstin, Loeffler, Markus, Kirsten, Holger, Peters, Annette, Scholz, Markus
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 23.05.2022 Public Library of Science (PLoS)
Subjects:	Analysis Biology and Life Sciences Biomarkers Cardiovascular disease Coronary heart disease Correlation CXCL16 protein Gene expression Gene loci Genes Genetic aspects Genomes Genotype & phenotype Health aspects Interleukin 6 Interleukin 6 receptors Medicine and Health Sciences Protein expression Proteins Proteomics Risk factors Tissues Germany
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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