Comparative phenotypic and functional analysis of migratory dendritic cell subsets from human oral mucosa and skin

Antigen exposure to oral mucosa is generally thought to lead to immune tolerance induction. However, very little is known about the subset composition and function of dendritic cells (DC) migrating from human oral mucosa. Here we show that migratory DC from healthy human gingival explants consist of...

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Vydáno v:	PloS one Ročník 12; číslo 7; s. e0180333
Hlavní autoři:	Kosten, Ilona Jennifer, van de Ven, Rieneke, Thon, Maria, Gibbs, Susan, de Gruijl, Tanja D.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 13.07.2017 Public Library of Science (PLoS)
Témata:	Analysis Antigens Antigens, CD1 - metabolism Bacteria Biology and Life Sciences Cell Differentiation Cell Movement Chemokines CXCR4 protein Cytokines Cytokines - metabolism Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Dermatology Differentiation (biology) Explants Frequency distribution Functional analysis Gingiva Health aspects Humans Immunity Immunization Immunological tolerance Inflammation Langerhans Cells - cytology Langerhans Cells - immunology Lymphatic system Lymphocytes Lymphocytes T Medicine and Health Sciences Mouth Mucosa - cytology Mouth Mucosa - metabolism Mucosa Mucous membrane Oral mucosa Phenotype Receptors, CXCR4 - metabolism Risk factors Skin Skin - cytology Skin - metabolism Steady state T cell receptors T-Lymphocytes - immunology Netherlands
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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