Additive Functions in Boolean Models of Gene Regulatory Network Modules

Gene-on-gene regulations are key components of every living organism. Dynamical abstract models of genetic regulatory networks help explain the genome's evolvability and robustness. These properties can be attributed to the structural topology of the graph formed by genes, as vertices, and regu...

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Veröffentlicht in:	PloS one Jg. 6; H. 11; S. e25110
Hauptverfasser:	Darabos, Christian, Di Cunto, Ferdinando, Tomassini, Marco, Moore, Jason H., Provero, Paolo, Giacobini, Mario
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 21.11.2011 Public Library of Science (PLoS)
Schlagworte:	Animal models Animals Astrobiology Biochemistry Biological effects Biology Biotechnology Boolean algebra Cell Cycle - genetics Computer Simulation Embryonic stem cells Embryonic Stem Cells - metabolism Experimental research Gene expression Gene Regulatory Networks - genetics Genes Genetics Genomes Graph theory Laboratories Mathematical models Mathematics Mice Models, Genetic Molecular biology Network topologies Networks Neural networks Organisms Phase transitions Reproducibility of Results Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - genetics Simulation Solution space Stem cells Structural stability Topology Transcription factors Yeast Lebanon Italy United States > US New Hampshire
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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