Stem Cell Factor Expression after Renal Ischemia Promotes Tubular Epithelial Survival

Renal ischemia leads to apoptosis of tubular epithelial cells and results in decreased renal function. Tissue repair involves re-epithelialization of the tubular basement membrane. Survival of the tubular epithelium following ischemia is therefore important in the successful regeneration of renal ti...

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Vydáno v:	PloS one Ročník 5; číslo 12; s. e14386
Hlavní autoři:	Stokman, Geurt, Stroo, Ingrid, Claessen, Nike, Teske, Gwendoline J. D., Weening, Jan J., Leemans, Jaklien C., Florquin, Sandrine
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 21.12.2010 Public Library of Science (PLoS)
Témata:	Animals Antisense oligonucleotides Apoptosis Autocrine signalling Basement Membrane - metabolism c-Kit protein Cell Biology/Cell Signaling Cell Biology/Cellular Death and Stress Responses Cell Survival Epidermal growth factor Epithelial cells Epithelial Cells - cytology Epithelium Gene Expression Regulation Hypoxia Immunology/Immune Response Ischemia Ischemia - pathology Kidney - pathology Kidney Tubules - metabolism Kidneys Kinases Ligands Male Mice Mice, Inbred C57BL Nephrology/Acute Renal Failure Oligonucleotides Phosphorylation Proto-Oncogene Proteins c-kit - metabolism Regeneration Renal function Reperfusion Rodents Stem cell factor Stem Cell Factor - biosynthesis Stem cells Survival Tubular basement membrane Netherlands
ISSN:	1932-6203, 1932-6203
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