Spectrum of gluten-related disorders: consensus on new nomenclature and classification

A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10 years, key milestones have moved celiac disease from obscurity into the popular spotlight worldwide. Now we are observing another interestin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC medicine Jg. 10; H. 1; S. 13
Hauptverfasser: Sapone, Anna, Bai, Julio C, Ciacci, Carolina, Dolinsek, Jernej, Green, Peter HR, Hadjivassiliou, Marios, Kaukinen, Katri, Rostami, Kamran, Sanders, David S, Schumann, Michael, Ullrich, Reiner, Villalta, Danilo, Volta, Umberto, Catassi, Carlo, Fasano, Alessio
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London BioMed Central 07.02.2012
BioMed Central Ltd
Springer Nature B.V
BMC
Schlagworte:
Allergies
Amino Acid Sequence
Autoimmune Diseases - classification
Autoimmune Diseases - diet therapy
Autoimmune Diseases - epidemiology
Biomedicine
Celiac disease
Celiac Disease - classification
Celiac Disease - diet therapy
Celiac Disease - epidemiology
Diet
Diet therapy
Diet, Gluten-Free
Gluten-free diet
Glutens - adverse effects
Glutens - chemistry
Health aspects
Humans
Hypersensitivity, Delayed - classification
Hypersensitivity, Delayed - diet therapy
Hypersensitivity, Delayed - epidemiology
Intestinal Diseases - classification
Intestinal Diseases - diet therapy
Intestinal Diseases - epidemiology
Medicine
Medicine & Public Health
Molecular Sequence Data
Opinion
Prevalence
Proteins
Wheat Hypersensitivity - classification
Wheat Hypersensitivity - diet therapy
Wheat Hypersensitivity - epidemiology
United States
Italy
Argentina
Celiac Disease
Autism Spectrum Disorder
Food Allergy
Human Leukocyte Antigen
Irritable Bowel Syndrome
ISSN:1741-7015, 1741-7015
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10 years, key milestones have moved celiac disease from obscurity into the popular spotlight worldwide. Now we are observing another interesting phenomenon that is generating great confusion among health care professionals. The number of individuals embracing a gluten-free diet (GFD) appears much higher than the projected number of celiac disease patients, fueling a global market of gluten-free products approaching $2.5 billion (US) in global sales in 2010. This trend is supported by the notion that, along with celiac disease, other conditions related to the ingestion of gluten have emerged as health care concerns. This review will summarize our current knowledge about the three main forms of gluten reactions: allergic (wheat allergy), autoimmune (celiac disease, dermatitis herpetiformis and gluten ataxia) and possibly immune-mediated (gluten sensitivity), and also outline pathogenic, clinical and epidemiological differences and propose new nomenclature and classifications.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ISSN:1741-7015
1741-7015
DOI:10.1186/1741-7015-10-13