Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer

Delta-like ligand 4 (Dll4) is a Notch ligand that is predominantly expressed in the endothelium. Evidence from xenografts suggests that inhibiting Dll4 may overcome resistance to antivascular endothelial growth factor therapy. The aims of this study were to characterize the expression of Dll4 in bre...

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Bibliographic Details
Published in:	The American journal of pathology Vol. 176; no. 4; p. 2019
Main Authors:	Jubb, Adrian M, Soilleux, Elizabeth J, Turley, Helen, Steers, Graham, Parker, Andrew, Low, Irene, Blades, Jennifer, Li, Ji-Liang, Allen, Paul, Leek, Russell, Noguera-Troise, Irene, Gatter, Kevin C, Thurston, Gavin, Harris, Adrian L
Format:	Journal Article
Language:	English
Published:	United States 01.04.2010
Subjects:	Aged Breast - pathology Breast Neoplasms - pathology Cell Line, Tumor Disease-Free Survival Endothelium - pathology Female Hemangiosarcoma - pathology Humans Immunohistochemistry In Situ Hybridization Inflammation Intercellular Signaling Peptides and Proteins - biosynthesis Intercellular Signaling Peptides and Proteins - physiology Middle Aged Prognosis
ISSN:	1525-2191, 1525-2191
Online Access:	Get more information
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