Genomic Confirmation of Borrelia garinii , United States

Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing...

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Published in:Emerging infectious diseases Vol. 29; no. 1; pp. 64 - 69
Main Authors: Rudenko, Natalie, Golovchenko, Maryna, Horak, Ales, Grubhoffer, Libor, Mongodin, Emmanuel F., Fraser, Claire M., Qiu, Weigang, Luft, Benjamin J., Morgan, Richard G., Casjens, Sherwood R., Schutzer, Steven E.
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01.01.2023
Centers for Disease Control and Prevention
Subjects:
Analysis
Animals
bacteria
Biopsy
Borrelia
Borrelia burgdorferi
Borrelia burgdorferi Group - genetics
Borrelia garinii
Causes of
Chromosomes
Cloning
DNA sequencing
Genes
Genetic aspects
Genomes
Genomic Confirmation of
genomic conformation
Genomics
Identification and classification
Lyme disease
Lyme Disease - epidemiology
migrating hosts
Nucleotide sequencing
Peromyscus
Phylogenetics
Phylogeny
Phylogeography
Plasmids
rodents
United States
United States - epidemiology
Vector-borne diseases
Whole genome sequencing
United States
Canada
East Asia
Czech Republic
South Carolina
Newfoundland and Labrador
United States > US
Asia
Texas
Japan
Europe
Georgia
Newfoundland & Labrador Canada
North America
migrating hosts
Lyme disease
vector-borne infections
bacteria
United States
Borrelia garinii
genomic conformation
zoonoses
rodents
ISSN:1080-6040, 1080-6059, 1080-6059
Online Access:Get full text
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Abstract Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.
AbstractList Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.
Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the coast of Newfoundland and Labrador, Canada, is a cause of Lyme disease in Eurasia. We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.
Audience Professional
Academic
Author Morgan, Richard G.
Luft, Benjamin J.
Fraser, Claire M.
Schutzer, Steven E.
Horak, Ales
Mongodin, Emmanuel F.
Qiu, Weigang
Casjens, Sherwood R.
Rudenko, Natalie
Golovchenko, Maryna
Grubhoffer, Libor
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  surname: Schutzer
  fullname: Schutzer, Steven E.
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Copyright COPYRIGHT 2023 U.S. National Center for Infectious Diseases
Published 2023. This article is a U.S. Government work and is in the public domain in the USA.
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Issue 1
Keywords migrating hosts
Lyme disease
vector-borne infections
bacteria
United States
Borrelia garinii
genomic conformation
zoonoses
rodents
Language English
License Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
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Snippet Lyme disease is a multisystem disorder primarily caused by Borrelia burgdorferi sensu lato. However, B. garinii, which has been identified on islands off the...
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StartPage 64
SubjectTerms Analysis
Animals
bacteria
Biopsy
Borrelia
Borrelia burgdorferi
Borrelia burgdorferi Group - genetics
Borrelia garinii
Causes of
Chromosomes
Cloning
DNA sequencing
Genes
Genetic aspects
Genomes
Genomic Confirmation of
genomic conformation
Genomics
Identification and classification
Lyme disease
Lyme Disease - epidemiology
migrating hosts
Nucleotide sequencing
Peromyscus
Phylogenetics
Phylogeny
Phylogeography
Plasmids
rodents
United States
United States - epidemiology
Vector-borne diseases
Whole genome sequencing
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Title Genomic Confirmation of Borrelia garinii , United States
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